中国免疫学杂志2024，Vol.40Issue(9)：1969-1974,6.DOI:10.3969/j.issn.1000-484X.2024.09.029
肠-关节轴:肠黏膜免疫与类风湿关节炎的关系探讨
Gut-joint axis:Relationship between intestinal mucosal immunity and rheumatoid arthritis
摘要
Abstract
Rheumatoid arthritis(RA)is a type of chronic autoimmune disease with unknown etiology and inflammatory syno-vitis.The occurrence and development of RA are closely related to intestinal mucosal immunity.Imbalance of intestinal flora,impaired intestinal barrier integrity,production of local autoantibodies and changes of immune cells in the lamina propria are all potential risks of RA.We explored the relationship between intestinal mucosal immunity and RA(gut-joint axis)in detail,with respect to provide novel thought and theoretical basis for the treatment of RA.关键词
肠黏膜免疫/类风湿关节炎/免疫细胞/肠道菌群Key words
Intestinal mucosal immunity/Rheumatoid arthritis/Immune cells/Gut microbiota分类
医药卫生引用本文复制引用
冀鹏,沙舟,张薇,史丽云..肠-关节轴:肠黏膜免疫与类风湿关节炎的关系探讨[J].中国免疫学杂志,2024,40(9):1969-1974,6.基金项目
国家自然科学基金(82371812,82000014). （82371812,82000014）
