中国中西医结合杂志2024，Vol.44Issue(9)：1063-1071,9.DOI:10.7661/j.cjim.20240730.052
青年原发性高血压病中医证型与相关因素分析
Analysis of Chinese Medicine Syndrome Types and Related Factors in Young Patients with Essential Hypertension
摘要
Abstract
Objective To explore the relationship between Chinese medicine(CM)syndrome types and related factors in young patients with essential hypertension.Methods A cross-sectional study design was used to collect data from inpatients in the Cardiology Department of Xiyuan Hospital,China Academy of Chinese Medical Sciences,from December 2017 to December 2021.Logistic regression analysis was employed to explore the relevant relationships.Results A total of 202 young hypertensive inpatients were included in the study.The distribution of CM syndrome types were as follows:phlegm and blood stasis syndrome(51.98％),Yin deficiency and Yang hyperactivity syndrome(24.75％),Qi and blood deficiency syndrome(15.84％),Shen Yang deficiency syndrome(7.43％).Logistic regression analysis showed that the history of cerebral infarction,hypertension stage,low-density lipoprotein cholesterol(LDL-C)level,24-hour average systolic blood pressure(24 h ASBP),24-hour average pulse(24 h AP),daytime average pulse(dAP),and nighttime average pulse(nAP)had an impact on Qi and blood deficiency syndrome(P＜0.05).Hypertension stage,apolipoprotein B(Apo B)level,and maximum systolic blood pressure(max-SBP)affected Shen Yang deficiency syndrome(P＜0.05).The history of fatty liver,lower high-density lipoprotein cholesterol(HDL-C),higher LDL-C,higher glycosylated hemoglobin(HbA1c),lower estimated glomerular filtration rate(eGFR),24 h AP,and dAP affected phlegm and blood stasis syndrome(P＜0.05).Age,atherosclerosis,decreased LDL-C,decreased Apo B,increased HbA1c,nighttime average diastolic blood pressure(nADBP),and percent time elevation of diastolic blood pressure(PTE％-DBP)influenced Yin deficiency and Yang hyperactivity syndrome(P＜0.05).Conclusions Phlegm and blood stasis syndrome is the most common CM syndrome among young hypertensive inpatients.There is a significant correlation between CM syndrome types and age,medical history,hypertension stage,related serological markers,and ambulatory blood pressure indicators.关键词
青年高血压病/中医证型/相关因素/Logistic回归分析/中西医结合Key words
young hypertension/Chinese medicine syndrome types/related factors/Logistic regression analysis/integrative medicine引用本文复制引用
李晓雅,张静怡,胡岚清,孙长鑫,张晓囡,陈纪烨,刘龙涛..青年原发性高血压病中医证型与相关因素分析[J].中国中西医结合杂志,2024,44(9):1063-1071,9.基金项目
首都卫生发展科研专项(No.2022-2-4172) （No.2022-2-4172）
国家自然科学基金资助项目(No.81973689) （No.81973689）
北京市自然科学基金资助项目(No.7202176) （No.7202176）
国家中医药管理局青年岐黄学者支持项目[No.国中医药人教发(2020)7] （2020）
