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首页|期刊导航|Neural Regeneration Research|Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

Yiyang Qin Wenzhen Zhu Tingting Guo Yiran Zhang Tingting Xing Peng Yin Shihua Li Xiao-Jiang Li Su Yang

Neural Regeneration Research2025,Vol.20Issue(9):P.2655-2666,12.
Neural Regeneration Research2025,Vol.20Issue(9):P.2655-2666,12.DOI:10.4103/NRR.NRR-D-23-01666

Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

Yiyang Qin 1Wenzhen Zhu 1Tingting Guo 1Yiran Zhang 1Tingting Xing 1Peng Yin 1Shihua Li 1Xiao-Jiang Li 1Su Yang1

作者信息

  • 1. Guangdong Key Laboratory of Non-human Primate Research,Key Laboratory of CNS Regeneration(Ministry of Education),Guangdong–HongKong–Macao Institute of CNS Regeneration,Jinan University,Guangzhou,Guangdong Province,China
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摘要

关键词

androgen receptor/mesencephalic astrocyte-derived neurotrophic factor/mouse model/neurodegeneration/neuronal loss/neurotrophic factor/polyglutamine disease/protein misfolding/spinal and bulbar muscular atrophy/transcription factor

分类

医药卫生

引用本文复制引用

Yiyang Qin,Wenzhen Zhu,Tingting Guo,Yiran Zhang,Tingting Xing,Peng Yin,Shihua Li,Xiao-Jiang Li,Su Yang..Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology[J].Neural Regeneration Research,2025,20(9):P.2655-2666,12.

基金项目

supported by the National Key R&D Program of China,No.2021YFA0805200(to SY) (to SY)

the National Natural Science Foundation of China,No.31970954(to SY) (to SY)

two grants from the Department of Science and Technology of Guangdong Province,Nos.2021ZT09Y007,2020B121201006(both to XJL)。 (both to XJL)

Neural Regeneration Research

1673-5374

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