日用化学品科学2024，Vol.47Issue(10)：33-38,6.DOI:10.3969/j.issn.1006-7264.2024.10.006
解淀粉芽孢杆菌F-1的分离鉴定及其胞外产物的功效活性研究
Isolation and identification of Bacillus amyloliquefaciens F-1 and study on the efficacy and activity of its extracellular products
张永涛 1谢松霖 1陈彬和 1魏娜 1吕智 1屠一栋1
作者信息
- 1. 上海相宜本草化妆品股份有限公司,上海 200444
- 折叠
摘要
Abstract
Bacillus amyloliquefaciens strain F-1 was isolated from fermented bean curd in laboratory.The extracellular products secreted by B.amyloliquefaciens strain F-1 are rich in protein and polysaccharide.To explore the potential efficacy and application value of the extracellular products,the antibacterial activity,antioxidant activity and anti-inflammatory activity were investigated by antibacterial test,free radical scavenging test and cell test.The results showed that 2%of the extracellular products could inhibit the growth of Cutibacterium acnes and scavenge nearly 50%of DPPH free radicals(IC50=2.776%).At the cellular level,the extracellular products showed strong anti-oxidative stress and anti-inflammatory capabilities.The concentration of 0.01%had the strongest effect on the reduction of HFF-1 reactive oxygen species induced by H2O2,and the extracellular products could significantly reduce the interleukin-factor 6 and interleukin-factor 10 of secreted by RAW264.7 within 0.1%concentration.关键词
解淀粉芽孢杆菌/胞外产物/抑菌/抗氧化/抗炎Key words
Bacillus amyloliquefaciens/extracellular products/antibacterial/antioxidant,anti-inflammatory分类
化学化工引用本文复制引用
张永涛,谢松霖,陈彬和,魏娜,吕智,屠一栋..解淀粉芽孢杆菌F-1的分离鉴定及其胞外产物的功效活性研究[J].日用化学品科学,2024,47(10):33-38,6.
