四川精神卫生2024，Vol.37Issue(5)：391-395,5.DOI:10.11886/scjsws20240523003
创伤后应激障碍快感缺失症状的研究进展
Research advances in anhedonia symptoms of post-traumatic stress disorder
摘要
Abstract
Anhedonia is defined as the reduction of pleasure and reward-seeking behavior,and it is prevalent in approximately two-thirds of individuals diagnosed with post-traumatic stress disorder(PTSD).Numerous empirical studies have consistently demonstrated that anhedonia represents an independent symptom dimension of PTSD.Furthermore,additional investigations have revealed that anhedonia plays a crucial role in the psychopathology of PTSD,contributing to the maintenance of post-traumatic stress responses,as well as more severe functional impairment and reduced therapeutic responsiveness.This paper aims to discuss the definition,psychopathology,genetic mechanisms and neurobiological underpinnings of anhedonia in PTSD,thus providing insights for future research on anhedonic symptoms.关键词
创伤后应激障碍/快感缺失/心理病理/神经影像/遗传Key words
Post-traumatic stress disorder/Anhedonia/Psychopathology/Nneuroimaging/Genetic mechanisms分类
临床医学引用本文复制引用
万嘉琛,李根,曹成琦,王力..创伤后应激障碍快感缺失症状的研究进展[J].四川精神卫生,2024,37(5):391-395,5.基金项目
国家自然科学基金联合基金重点项目支持(项目名称:COVID-19相关的创伤后应激障碍的发病机制及干预策略研究,项目编号:U21A20364) （项目名称:COVID-19相关的创伤后应激障碍的发病机制及干预策略研究,项目编号:U21A20364）
国家自然科学基金青年项目(项目名称:创伤后应激障碍闯入症状簇的异质性:来自心理病理、分子遗传和神经内分泌的证据,项目编号:32300918) Funded by National Natural Science Foundation of China Joint Fund Key Project(number,U21A20364) （项目名称:创伤后应激障碍闯入症状簇的异质性:来自心理病理、分子遗传和神经内分泌的证据,项目编号:32300918）
National Natural Science Foundation of China Youth Fund(number,32300918) （number,32300918）
