现代科学仪器2024，Vol.41Issue(5)：40-45,6.
两种国产膀胱癌荧光原位杂交检测试剂盒的临床应用比对
Comparative clinical application of two domestic fluorescence in situ hybridization kits in bladder cancer
张家淮 1高朋 1陈佳静 1颜乐 1赵炜 1史秦峰2
作者信息
- 1. 首都医科大学临床检验中心,北京 100069
- 2. 首都医科大学基础医学院病理学系,北京 100069
- 折叠
摘要
Abstract
Objective:Comparing the detection results of malignant urothelial cells isolated from voided urine between two domestic Fluorescence In Situ Hybridization(FISH)kits and probe the potential clinical value of FISH.Methods:Urine of 20 patients were collected from Center for Clinical Laboratory,Capital Medical University between January 2021 to January 2022.We used different domestic kits to test the different results of chromosomal aberrations and then compared with CellDetect® staining.Results:Only one patient with the test results of two domestic kits were inconsistent.And the results show that the remaining patients were consistent with the assay result(P>0.05).The positive detection rates of the two kits were 50%and 45%,respectively.Conclusion:We found that the high concordance of the results of chromosomal aberrations with two different FISH kits and both kits can be detected bladder cancer in clinical laboratories.关键词
膀胱癌/荧光原位杂交/CellDetect染色Key words
bladder cancer/fluorescence in situ hybridization/CellDetect staining引用本文复制引用
张家淮,高朋,陈佳静,颜乐,赵炜,史秦峰..两种国产膀胱癌荧光原位杂交检测试剂盒的临床应用比对[J].现代科学仪器,2024,41(5):40-45,6.
