现代科学仪器2024,Vol.41Issue(5):171-175,5.
达格列净对不同左心室射血分数心衰患者疗效及预后研究
Study on the efficacy and prognosis of dapagliflozin in patients with heart failure with different left ventricular ejection fractions
谢倩倩 1徐飞 1周勇1
作者信息
- 1. 安徽医科大学附属宿州医院心内科,安徽宿州 234000
- 折叠
摘要
Abstract
Objective:To analyze the efficacy and prognostic impact of dapagliflozin on heart failure patients with different left ventricular ejection fractions.Method:200 heart failure patients with varying left ventricular ejection fractions,admitted between October 2022 to November 2023,were selected and categorized into two groups based on their ejection fractions:>40%and≤40%.Both groups received dapagliflozin alongside conventional treatment.Various parameters,including renal function and BNP levels,were assessed after 3 months,followed by a 6-month follow-up.Results:Significant improvements were observed in renal function,BNP levels,cardiac structural parameters,BMI,6-minute walk distance,resting heart rate,and the incidence of various complications in both groups after dapagliflozin treatment(P<0.05).The post-treatment indicators were similar between the two groups(P>0.05).Conclusion:Dapagliflozin demonstrates effective treatment for heart failure patients across various left ventricular ejection fractions,with its efficacy and prognosis unaffected by the ejection fraction.关键词
达格列净/左心室射血分数/心力衰竭Key words
Daggligin/Left Ventricular Ejection Fraction/Heart Failure分类
医药卫生引用本文复制引用
谢倩倩,徐飞,周勇..达格列净对不同左心室射血分数心衰患者疗效及预后研究[J].现代科学仪器,2024,41(5):171-175,5.