现代科学仪器2024，Vol.41Issue(5)：176-180,5.
iTBS、tDCS对精神分裂症患者躯体-社会快感缺失的影响
Effects of iTBS and tDCS on somatosocial anhedonia in patients with schizophrenia
龚莹莹 1姜庆伟 1江庐山1
作者信息
- 1. 常州市德安医院精神科,江苏常州 213000
- 折叠
摘要
Abstract
Objective:To observe the effects of intermittent theta burst stimulation(iTBS)and transcranial direct current stimulation(tDCS)on somatosocial anhedonia in patients with schizophrenia.Methods:91 schizophrenic patients were randomly divided into iTBS group(47 cases)and tDCS group(44 cases),and given iTBS treatment and tDCS treatment respectively.The scores of Somatic anhedonia Scale(RPAS-C),Social Pleasure Scale(RSAS-C),Positive and Negative Symptom Scale(PANSS)and the levels of related neurotransmitters in the left forebrain were compared between the two groups before and after treatment.Results:RPAS-C,RSAS-C,negative symptom,general psychopathological symptom score and PANSS total score after treatment were lower than before treatment(P<0.05),Glu,DA and GABA levels in left forebrain area were higher than before treatment(P<0.05).The improvement of the above indexes in iTBS group was better than that in tDCS group(P<0.05).Conclusion:Both iTBS and tDCS can effectively improve anhedonia symptoms in patients with schizophrenia,and iTBS is more effective than tDCS.关键词
间歇性θ波爆发刺激/经颅直流电刺激/精神分裂症/快感缺失/脑神经递质Key words
Intermittent theta burst stimulation/Transcranial direct current stimulation/Schizophrenia/Anhedonia/Brain neurotransmitters引用本文复制引用
龚莹莹,姜庆伟,江庐山..iTBS、tDCS对精神分裂症患者躯体-社会快感缺失的影响[J].现代科学仪器,2024,41(5):176-180,5.
