现代科学仪器2024，Vol.41Issue(5)：195-199,5.
AFP、VEGF及HSP70在原发性肝癌中的表达及对预后的预测价值
Expression of AFP,VEGF and HSP70 in primary liver cancer and their prognostic value
摘要
Abstract
Objective:To investigate the expression of serum AFP,VEGF,and HSP70 in primary liver cancer and their predictive value for prognosis.Method:110 cases of primary liver cancer and 50 healthy individuals were selected as the study group and control group,respectively.Based on the prognosis within one year after surgery,the study group was divided into a good prognosis group and a poor prognosis group.The differences in serum AFP,VEGF,and HSP70 expression were compared to evaluate their diagnostic efficacy for poor prognosis.Result:The serum levels of AFP,VEGF,and HSP70 in the study group were higher than those in the control group,and those in the poor prognosis group were higher than those in the good prognosis group(P<0.05);The AUC for predicting poor prognosis in patients with primary liver cancer using serum AFP,VEGF,and HSP70 is 0.981.Conclusion:Serum AFP,VEGF,and HSP70 can predict poor prognosis in patients with primary liver cancer.关键词
原发性肝癌/预后Key words
primary liver cancer/prognosis分类
医药卫生引用本文复制引用
徐兴军,芦东徽,马欢,高世乐,王冬梅..AFP、VEGF及HSP70在原发性肝癌中的表达及对预后的预测价值[J].现代科学仪器,2024,41(5):195-199,5.基金项目
安徽省卫生健康委科研项目(AHWJ2022b070) （AHWJ2022b070）
