眼科学报2024，Vol.39Issue(8)：416-423,8.DOI:10.12419/24070109
儿童Ⅱ期人工晶状体植入术后青光眼相关不良事件影响因素与预测的研究进展
Research progress on associated factors and prediction of glaucoma-related adverse events following secondary intraocular lens implantation in pediatric eyes
摘要
Abstract
Pediatric cataract is one of the leading causes of treatable childhood blindness worldwide.For these children,surgery is the primary method to restore or preserve vision.However,postoperative complications,particularly glaucoma-related adverse events(GRAEs),often become the main reason for secondary blindness in children,attracting widespread concern in the field of ophthalmology.This study reviews the impact factors of glaucoma-related adverse events after secondary intraocular lens(IOL)implantation in children,including surgical design,ocular anatomical characteristics,other ocular developmental abnormalities,and systemic diseases.Whether to implant an IOL in the surgical design and the timing and positioning of the implantation have a significant impact on the occurrence of GRAEs.In addition,ocular anatomical characteristics,such as corneal diameter,axial length,anterior chamber depth,central corneal thickness,and preoperative lens thickness,are also important factors affecting the occurrence of GRAEs.At the same time,other ocular developmental abnormalities and systemic diseases,such as congenital aniridia and congenital rubella syndrome,also increase the incidence of glaucoma after pediatric cataract surgery.The article also summarizes methods for predicting GRAEs and recommends using the Cox regression model to establish a predictive model.This model can effectively predict the probability of children developing GRAEs after secondary IOL implantation within a specific time period,providing an important reference for the early identification of high-risk children for GRAEs.Through in-depth analysis of the impact factors of GRAEs and the establishment of predictive models,the article aims to help ophthalmologists better understand the mechanisms of GRAEs and assess the risks of children before surgery,thereby selecting the best surgical plan and preventive measures.This is of great clinical significance for improving postoperative recovery in children,reducing complications,and protecting visual function.关键词
儿童白内障/Ⅱ期IOL植入术/术后并发症/青光眼相关不良事件/多因素回归模型Key words
pediatric cataract/secondary IOL implantation/postoperative complications/glaucoma-related adverse events/multifactorial regression model分类
医药卫生引用本文复制引用
徐超群,陈惠,刘臻臻..儿童Ⅱ期人工晶状体植入术后青光眼相关不良事件影响因素与预测的研究进展[J].眼科学报,2024,39(8):416-423,8.基金项目
广东省自然科学基金(2023A1515011102) （2023A1515011102）
广州市院校联合项目(2023A03J0174 （）
2023A03J0188).This work was supported by the Natural Science Foundation of Guangdong Province,China(2023A1515011102)and the grant from the Municipal Government and School(Hospital)Joint Funding Program of Guangzhou(2023A03J0174,2023A03J0188). （2023A1515011102）
