超声心动图评估无导线起搏器Micra AV植入后的心肌应变及心室不同步性OACSTPCD
Echocardiography evaluation of myocardial strain and ventricular dyssynchrony after implantation of leadless pacemaker Micra AV
目的 探讨植入Micra AV无导线起搏器患者的左、右室心肌应变及不同步性,并进一步分析植入位置对心肌应变及不同步性的影响.方法 回顾性选择 2023 年 4 月至 2023 年 12 月在复旦大学附属中山医院心内科植入Micra AV的患者 43 例(Micra AV组)以及高度房室传导阻滞(Ⅱ度Ⅱ型、Ⅲ度房室传导阻滞)患者 20 例(传导阻滞组),收集患者人口学信息、临床特征.采用常规超声心动图和斑点追踪成像技术获取 2 组患者的常规心超参数、心肌应变及不同步性指标,包括心室整体纵向应变(global longitudinal strain,GLS)、心室游离壁纵向应变(free wall longitudinal strain,FWLS)、左室 18 节段纵向应变达峰时间离散度(peak strain dispersion,PSD)、右室 6 节段PSD以及其他指标.根据Micra AV植入位置进一步分为中位组(右室间隔部)、高位组(右室流入道)及低位组(心尖部),比较 3 个亚组心肌应变及不同步性指标差异.结果 Micra AV组左室GLS、右室GLS、右室FWLS均显著低于传导阻滞组(P<0.001),Micra AV组的右室不同步性显著高于传导阻滞组(P<0.05).不同植入部位心肌应变及不同步性比较显示,高位组左室GLS显著高于中位组和低位组,左室不同步性指标Yu指数显著低于中位组(P<0.05);低位组右室射血分数(right ventricular ejection fraction,RVEF)显著低于高位组,右室 6 节段PSD显著高于中位组和高位组(P<0.05).结论 与高度房室传导阻滞患者相比,Micra AV无导线起搏患者的左室及右室心肌应变减低,且低位植入的影响更大.
Objective To explore the left and right ventricular myocardial strain and dyssynchrony in patients with Micra AV leadless pacing implantation,and to further analyze the impact of implantation site on myocardial strain and dyssynchrony.Methods A retrospective study was conducted on 43 patients with Micra AV implantation and 20 patients with high-degree atrioventricular block(Ⅱdegree typeⅡandⅢdegree atrioventricular block)at the Department of Cardiology,Zhongshan Hospital from April 2023 to December 2023.The demographic information and clinical characteristics of the patients were collected.Echocardiography and speckle tracking imaging techniques were used to obtain conventional echocardiographic parameters,myocardial strain,and dyssynchrony indices of patients in the two groups,including global longitudinal strain(GLS),free wall longitudinal strain(FWLS),peak strain dispersion(PSD)of 18 left ventricular segments,PSD of 6 right ventricular segments,and other indices.According to the implantation location of Micra AV,the patients were further divided into middle group(right ventricular septum),high group(right ventricular inflow tract),and low group(apical region),and the differences in myocardial strain and dyssynchrony indices among the three subgroups were compared.Results The left ventricular GLS(LVGLS),right ventricular GLS(RVGLS),and right ventricular FWLS(RVFWLS)of the Micra AV group were significantly lower than those of the conduction block group(P<0.001),and the right ventricular dyssynchrony of the Micra AV group was significantly higher than that of the conduction block group(P<0.05).Comparison of myocardial strain and dyssynchrony at different implantation sites showed that the LVGLS of the high implantation group was significantly higher than that of the middle and low implantation groups,and the left ventricular dyssynchrony index Yu was significantly lower than that of the middle group(P<0.05);the right ventricular ejection fraction(RVEF)of the low implantation group was significantly lower than that of the high group,and the right ventricular 6-segment PSD was significantly higher than that of the middle and high implantation groups(P<0.05).Conclusions Compared with patients with high-degree atrioventricular block,patients with Micra AV leadless pacing have reduced left and right ventricular strain,and the implantation of low position had greater effect.
孜比热·甫拉提;禹子清;刘雯;陈海燕;舒先红
复旦大学附属中山医院心脏超声诊断科,上海 200032复旦大学附属中山医院心内科,上海 200032
临床医学
Micra AV无导线起搏器心肌应变心室不同步性斑点追踪成像技术
Micra AVleadless pacemakermyocardial strainventricular dyssynchronyspeckle tracking imaging
《中国临床医学》 2024 (005)
705-711 / 7
国家自然科学基金(82471997,82227803,82202178),复旦大学医工结合重点项目(IDH2310146).Supported by National Natural Science Foundation of China(82471997,82227803,82202178)and Fudan University Key Project in Medical Engineering Integration(IDH2310146).
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