中国临床医学2024，Vol.31Issue(5)：804-810,7.DOI:10.12025/j.issn.1008-6358.2024.20240850
基于CT的3D定量形状特征对原发性胃肠道间质瘤术后无病生存期的预测价值
Predictive value of 3D quantitative shape features based on CT for disease-free survival of primary gastrointestinal stromal tumors
摘要
Abstract
Objective To explore the predictive value of 3D quantitative shape features based on enhanced CT for disease-free survival(DFS)of primary gastric gastrointestinal stromal tumors(GIST)patients receiving curative resection.Methods From January 2010 to December 2016,a total of 154 patients with primary gastric GIST who received curative resection in Zhongshan Hospital,Fudan University were retrospectively collected.The conventional CT imaging features and 3D quantitative shape features of tumors were evaluated,and the influencing factors of DFS were analyzed by univariate and multivariate Cox regression.Cut-off values were extracted,and Kaplan-Meier curves were used for survival analysis.Results Maximum 3D diameter(HR=1.829,95% CI 1.389-2.408,P＜0.001)and spherical disproportion(HR=2.153,95% CI 1.474-3.146,P＜0.001)were independent risk factors for DFS in primary gastric GIST.Kaplan-Meier curves showed that patients with maximum 3D diameter＞90.5 mm and spherical disproportion＞1.5 showed shorter DFS after curative resection(P＜0.001).Conclusion Maximum 3D diameter and spherical disproportion based on preoperative enhanced CT are valuable in the diagnosis of postoperative DFS in primary gastric GIST.关键词
胃肠道间质瘤/计算机断层成像/无病生存期/最大三维直径/球面歧化Key words
gastrointestinal stromal tumors/computed tomography/disease-free survival/maximum 3D diameter/spherical disproportion分类
医药卫生引用本文复制引用
陈晓姗,陈杰军,杨雨涛,周建军,饶圣祥..基于CT的3D定量形状特征对原发性胃肠道间质瘤术后无病生存期的预测价值[J].中国临床医学,2024,31(5):804-810,7.基金项目
中华国际医学交流基金会 2020 SKY影像科研基金(Z-2014-07-2003-04).Supported by 2020 SKY Imaging Research Foundation of China International Medical Foundation(Z-2014-07-2003-04). （Z-2014-07-2003-04）
