中国临床医学2024，Vol.31Issue(5)：819-825,7.DOI:10.12025/j.issn.1008-6358.2024.20240024
脂质代谢在年龄相关性黄斑变性发病机制中的研究进展
Research progress of lipid metabolism in the pathogenesis of age-related macular degeneration
商宇 1邹蓉 1袁源智1
作者信息
- 1. 复旦大学附属中山医院眼科,上海 200032
- 折叠
摘要
Abstract
Age-related macular degeneration(AMD)is the first permanent cause of vision loss in developed countries,which is also a disease with high incidence and blindness rate in China.Studies have demonstrated that lipid metabolism is one of the key mechanisms of AMD.However,the precise mechanism remains unclear and medications for AMD treatments based on this mechanism have not yet been established.In this review,we critically review relevant studies to examine the associations between lipid metabolism and AMD from the perspectives of lipoproteins,lipid metabolism-related molecular,and lipid metabolism-related treatments,aiming to help understand the roles that lipid metabolism mechanisms play in the development and progression of AMD and to provide ideas for future targeted lipid metabolism therapies.关键词
年龄相关性黄斑变性/脂质代谢/脂蛋白Key words
age-related macular degeneration/lipid metabolism/lipoprotein分类
医药卫生引用本文复制引用
商宇,邹蓉,袁源智..脂质代谢在年龄相关性黄斑变性发病机制中的研究进展[J].中国临床医学,2024,31(5):819-825,7.
