中医药信息2024，Vol.41Issue(10)：64-76,13.DOI:10.19656/j.cnki.1002-2406.20241012
黄连化学成分、药理作用及配伍应用的研究进展
Research Progress on the Chemical Constituents,Pharmacological Actions,and Compatibility Applications of Coptis Chinensis
摘要
Abstract
Coptis chinensis,the dried rhizome of a perennial herb from the Ranunculaceae family,has a long history of medicinal use,particularly in the treatment of dysentery,eczema,and acute gastroenteritis.A review of relevant literature reveals that the main chemical constituents of the medicinal include alkaloids,lignans,flavonoids,and acidic substances.These compounds exhibit a variety of pharmacological effects such as hypoglycemic,cardiovascular improvement,anti-inflammatory,antitumor,antibacterial,digestive system improvement,and sedative-hypnotic actions.Compatibility studies of Coptis chinensis formulations highlight that formulae combined with this medicinal can be used in treating various syndromes,such as five damp-heat syndromes,fourteen fire-toxin and heat excess syndromes,four sores and carbuncles syndromes,and eight yin-yang imbalance syndromes.Berberine,one of the most extensively and systematically studied components of Coptis chinensis,has been a focal point of research.However,at present,there is relatively little research on the corresponding relationship of the other active ingredients and the chemical components in coptis chinensis of ancient Chinese herbal formulas with mechanisms of action.关键词
黄连/化学成分/药理作用/配伍应用Key words
Coptis chinensis/Chemical constituents/Pharmacological actions/Compatibility applications引用本文复制引用
沈子扬,韩宇博,刘树民,于栋华..黄连化学成分、药理作用及配伍应用的研究进展[J].中医药信息,2024,41(10):64-76,13.基金项目
国家自然科学基金项目(82205060) （82205060）
