术中超声在脑胶质瘤切除术中应用价值的Meta分析OACSTPCD

Objective:To systematically evaluate the total resection rate and operation time of glioma resection surgery guided by intraoperative ultrasound(IOUS),and the prognosis of patients.Methods:The literature about the application of IOUS in the resection of glioma was searched from the databases including CNKI,Wan Fang,VIP,CBM,PubMed,Web of Sci-ence,Embase and the Cochrane Library from the establishment of the database to December 2022.After rigorous evaluation and data extraction by two evaluators independently,meta-analysis was conducted by Review Manager 5.4.Results:Sixteen articles with a total of 1,573 cases were included.In the total resection rate,surgical duration,l-year survival rate,and 2-year survival rate,there were statistically significant differences between the IOUS group and the control group(RR=1.41,95％CI:1.27～1.56,P＜0.001;SMD=-0.56,95％CI:-0.74～-0.38,P＜0.001;RR=1.35,95％CI:1.19～1.53,P＜0.001;RR=1.63,95％CI:1.34～2.00,P＜0.001).Conclusion:Glioma resection surgery guided by IOUS can improve the total resection rate,shorten the surgical duration,and improve the 1-and 2-year survival rates of the patients.