首页|期刊导航|中国临床药理学杂志|阿替普酶联合利伐沙班治疗老年肥胖患者急性下肢深静脉血栓的临床研究

阿替普酶联合利伐沙班治疗老年肥胖患者急性下肢深静脉血栓的临床研究OA北大核心CSTPCD

Clinical trial of alteplase combined with rivaroxaban in the treatment of elderly obese patients with acute lower extremity deep vein thrombosis

中文摘要英文摘要

目的 观察阿替普酶注射液联合利伐沙班片治疗老年肥胖患者急性下肢深静脉血栓(DVT)的临床疗效及安全性.方法 将老年肥胖合并DVT患者按随机数字表法分为对照组和试验组.对照组给予10 mg·d-1利伐沙班片治疗,口服.试验组在对照组治疗的基础上,联合0.9 mg·kg-1·d-1注射阿替普酶治疗,静脉给药.2组患者均治疗1周.比较2组患者的临床疗效、凝血功能指标、下肢静脉血流动力学指标、炎症因子及血管内皮功能相关指标、miR-374b-5p相对表达…查看全部>>

Objective To observe the clinical efficacy and safety of alteplase combined with rivaroxaban in the treatment of acute deep vein thrombosis(DVT)in elderly obese patients.Methods Elderly obese patients with DVT were divided into control group and treatment group according to random number table method.The control group was treated with 10 mg·d-1 rivaroxaban tablets orally.The treatment group was treated with 0.9 mg·kg-1·d-1 alteplase on the basis of the contr…查看全部>>

贾亚男;王雅琼;郭立新;唐灵涛

邢台市中心医院心血管外科,河北邢台 054000邢台市中心医院心血管外科,河北邢台 054000邢台市中心医院心脏大血管外科,河北邢台 054000邢台市中心医院神经内科,河北邢台 054000

药学

阿替普酶注射液利伐沙班片老年肥胖急性下肢深静脉血栓血小板活化功能

alteplase injectionrivaroxaban tabletold age obesityacute deep venous thrombosis of lower extremityplatelet activation function

《中国临床药理学杂志》 2024 (20)

2939-2943,5

10.13699/j.cnki.1001-6821.2024.20.006

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