北京中医药大学学报2024，Vol.47Issue(10)：1349-1354,6.DOI:10.3969/j.issn.1006-2157.2024.10.003
从"虚毒"探讨炎症性肠病"炎癌转化"
Discussion on"inflammation-cancer transformation"of inflammatory bowel disease from the perspective of"deficiency-toxin"theory
摘要
Abstract
As essential concepts of the traditional Chinese medicine theory,"deficiency"and"toxin"have been enriched and developed continuously since Huangdi Neijing.By tracing back and combing"deficiency"and"toxin",this paper sums up their relationship,analyzes and explains their basic connotation,and discusses their extension.The"deficiency-toxin"theory has two meanings:it covers the pathological state of the human body with deficiency of vital qi and excess of pathogenic toxin,and it also refers to the pathological evolutionary process in which"deficiency"and"toxin"promote each other.Based on the connotation and dynamic pathogenesis of the"deficiency-toxin"theory,it is pointed out that this theory can be applied to the prevention and treatment of infectious diseases and chronic debilitating diseases,including the"inflammation-cancer transformation"of inflammatory bowel disease.Taking inflammatory bowel disease as an example and combining its Western medical background,this paper expounds on the pathogenesis and treatment of the"inflammation-cancer transformation"of inflammatory bowel disease,and provides a paradigm of"deficiency-toxin"theory guiding clinical research.关键词
虚毒/炎癌转化/炎症性肠病Key words
deficiency-toxin/inflammation-cancer transformation/inflammatory bowel disease分类
医药卫生引用本文复制引用
魏秀楠,梁峻尉,孙大娟,张苗苗,迟莉丽..从"虚毒"探讨炎症性肠病"炎癌转化"[J].北京中医药大学学报,2024,47(10):1349-1354,6.基金项目
国家自然科学基金项目(No.81673969,No.82205057) （No.81673969,No.82205057）
济南市科技计划项目(No.202134024) （No.202134024）
山东中医药大学青年科研创新团队 National Natural Science Foundation of China(Nos.81673969 and 82205057) （Nos.81673969 and 82205057）
