临床小儿外科杂志2024，Vol.23Issue(9)：814-818,5.DOI:10.3760/cma.j.cn101785-202306037-003
直肠分层活检术在儿童顽固性便秘中的应用探讨
Application of stratified rectal biopsy for refractory constipation in children
摘要
Abstract
Objective To introduce a novel method of rectal full thickness biopsy and compare it with tra-ditional method to further improve the satisfaction of pathological sampling for refractory constipation(RC)in children.Methods From December 2019 to December 2022,a total of 269 RC children were hospitalized.Ac-cording to the inclusion criteria,the relevant clinical data were retrospectively reviewed for 217 cases.Traditional full thickness rectal biopsy(traditional group,n=92)and stratified rectal biopsy(stratified group,n=125)were performed.Baseline profiles,intraoperative findings and compliance rate of pathological sampling were compared between two groups.Results All operations were completed successfully.Operative age[(10.9±2.8)vs.(10.4±2.7)month],volume of blood loss[(4.6±1.9)vs.(5.1±1.7)ml]and postoperative hospitalization stay[(1.6±0.6)vs.(1.7±0.5)day]showed no significant inter-group differences(P＞0.05).Significant in-ter-group difference existed in compliance rate of sampling[88.0％(81/92)vs.100％(125/125)]and operative duration[(29.3±6.6)vs.(34.7±5.6)min](P＜0.05).Conclusions Stratified rectal biopsy may signifi-cantly improve the compliance rate of sampling and avoid pathological diagnostic difficulties of insufficient sam-pling.关键词
便秘/活组织检查/病理学,外科/儿童Key words
Constipation/Biopsy/Pathology,Surgical/Child引用本文复制引用
陶波圆,林瑞燕,陈凯,曾纪晓,刘斐,徐晓钢,兰梦龙,梁子建,钟知足,林玉珍..直肠分层活检术在儿童顽固性便秘中的应用探讨[J].临床小儿外科杂志,2024,23(9):814-818,5.基金项目
国家自然科学基金(82170528) （82170528）
广东省自然科学基金(2022A1515012254) （2022A1515012254）
广州市科技计划市校(院)联合资助项目(202201020612) （院）
广州市临床特色技术项目(2023C-TS48) （2023C-TS48）
卫生健康技术重点推广项目(XM202403895) National Natural Science Foundation of China(82170528) （XM202403895）
Natural Science Foundation of Guangdong Province(2022A1515012254) （2022A1515012254）
Guangzhou Municipal Science & Technology Plan of University(Institute)Joint Funding Project(202201020612) （Institute）
Guangzhou Municipal Clinical Characteristic Technology Project(2023C-TS48) （2023C-TS48）
Key Promotion Project of Health Technology(XM202403895) （XM202403895）
