中国实用妇科与产科杂志2024，Vol.40Issue(10)：994-1002,9.DOI:10.19538/j.fk2024100109
子痫前期基础研究新进展
New progress in basic research on preeclampsia
摘要
Abstract
The placenta is a temporary organ that plays an important role in maintaining fetal growth and de-velopment during pregnancy,as well as mediating maternal adaptation to pregnancy.Abnormalities in placental development and/or impaired function of the placenta will lead to pregnancy-related diseases,such as preeclampsia.Preeclampsia is a pregnancy-related disease that occurs after 20 weeks of pregnancy,characterized by clinical symptoms such as hyperten-sion and proteinuria.The etiology of preeclampsia is very complex,but previous studies have found that the main cause of preeclampsia is abnormal development and/or dysfunction of the placenta.The root cause of preeclampsia is the release of"toxic factors"into the maternal circulation by the dysfunctional placenta.Based on the normal development of the placenta and its regulatory mechanisms,this article discusses the models and techniques for research in preeclampsia,new advances in basic research and their potential application.关键词
胎盘发育/子痫前期/研究模型和技术手段/基础研究新进展Key words
placental development/preeclampsia/re-search models and techniques/new advances in ba-sic research分类
临床医学引用本文复制引用
鲁金花,王海滨..子痫前期基础研究新进展[J].中国实用妇科与产科杂志,2024,40(10):994-1002,9.基金项目
国家重点研发计划(2022YFC2702500,2021YFC2700302,2022YFC2704700,2022YFC2702400) （2022YFC2702500,2021YFC2700302,2022YFC2704700,2022YFC2702400）
国家自然科学基金(82288102,82171660) （82288102,82171660）
