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Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease

Hongli Li Jianhua Huang Di Zhao Lemei Zhu Zheyu Zhang Min Yi Weijun Peng

Neural Regeneration Research2025，Vol.20Issue(10)：P.2982-2997,16.

Neural Regeneration Research2025，Vol.20Issue(10)：P.2982-2997,16.DOI:10.4103/NRR.NRR-D-23-01979

Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease

Hongli Li ¹Jianhua Huang ²Di Zhao ²Lemei Zhu ³Zheyu Zhang ⁴Min Yi ⁴Weijun Peng¹

作者信息

1. Department of Integrated Traditional Chinese&Western Medicine,The Second Xiangya Hospital,Central South University,Changsha,Hunan Province,China National Clinical Research Center for Metabolic Diseases,Changsha,Hunan Province,China
2. Hunan Academy of Chinese Medicine,Changsha,Hunan Province,China
3. Academician Workstation,Changsha Medical University,Changsha,Hunan Province,China
4. Department of Integrated Traditional Chinese&Western Medicine,The Second Xiangya Hospital,Central South University,Changsha,Hunan Province,China
折叠

摘要

关键词

Alzheimer’s disease/APP/PS1 mice/brain-kidney axis/gut microbiota/heart-brain axis/liver-brain axis/lung-brain axis/microbiota-gut-brain axis/peripheral organ metabolism/spleen-brain axis

分类

医药卫生

引用本文复制引用

Hongli Li,Jianhua Huang,Di Zhao,Lemei Zhu,Zheyu Zhang,Min Yi,Weijun Peng..Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease[J].Neural Regeneration Research,2025,20(10):P.2982-2997,16.

基金项目

supported by the National Natural Science Foundation of China,No.82374552(to WP) （to WP）

the Science and Technology Innovation Program of Hunan Province,No.2022RC1220(to WP) （to WP）

the Natural Science Foundation of Hunan Province of China,Nos.2020JJ4803(to WP),2022JJ40723(to MY) （to WP）

the Scientific Research Launch Project for New Employees of the Second Xiangya Hospital of Central South University(to MY).How to cite this article:Li H,Huang J,Zhao D,Zhu L,Zhang Z,Yi M,Peng W(2025)Longitudinal assessment of peripheral organ metabolism and the gut microbiota in an APP/PS1 transgenic mouse model of Alzheimer’s disease.Neural Regen Res 20(10):2982-2997. （to MY）

Neural Regeneration Research

ISSN：1673-5374

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