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首页|期刊导航|Neural Regeneration Research|Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

Wei Zhang Yubao Lu Ruoqi Shen Yingjie Wu Chenrui Liu Xingxing Fang Liangming Zhang Bin Liu Limin Rong

Neural Regeneration Research2025,Vol.20Issue(10):P.2955-2968,14.
Neural Regeneration Research2025,Vol.20Issue(10):P.2955-2968,14.DOI:10.4103/NRR.NRR-D-23-01933

Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury

Wei Zhang 1Yubao Lu 1Ruoqi Shen 2Yingjie Wu 2Chenrui Liu 2Xingxing Fang 2Liangming Zhang 1Bin Liu 1Limin Rong1

作者信息

  • 1. Department of Spine Surgery,The Third Affiliated Hospital,Sun Yat-sen University,Guangzhou,Guangdong Province,China National Medical Products Administration(NMPA)Key Laboratory for Quality Research and Evaluation of Cell Products,Guangzhou,Guangdong Province,China Guangdong Provincial Center for Quality Control of Minimally Invasive Spine Surgery,Guangzhou,Guangdong Province,China Guangdong Provincial Center for Engineering and Technology Research of Minimally Invasive Spine Surgery,Guangzhou,Guangdong Province,China
  • 2. Department of Spine Surgery,The Third Affiliated Hospital,Sun Yat-sen University,Guangzhou,Guangdong Province,China
  • 折叠

摘要

关键词

ceramide synthase 5/gasdermin D/microglia/neuroinflammation/NLRP3/nuclear factor kappa B/Pla2g7/pyroptosis/sphingomyelin metabolism/spinal cord injury

分类

医药卫生

引用本文复制引用

Wei Zhang,Yubao Lu,Ruoqi Shen,Yingjie Wu,Chenrui Liu,Xingxing Fang,Liangming Zhang,Bin Liu,Limin Rong..Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury[J].Neural Regeneration Research,2025,20(10):P.2955-2968,14.

基金项目

supported by grants from the National Key Research and Development Program of China,No.2017YFA0105400(to LR) (to LR)

the Key Research and Development Program of Guangdong Province,No.2019B020236002(to LR) (to LR)

the National Natural Science Foundation of China,Nos.81972111(to LZ),81772349(to BL). (to LZ)

Neural Regeneration Research

1673-5374

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