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首页|期刊导航|Bone Research|Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects

Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects

Zhenqiang Yao Akram Ayoub Venkatesan Srinivasan Jun Wu Churou Tang Rong Duan Aleksa Milosavljevic Lianping Xing Frank H.Ebetino Alison J.Frontier Brendan F.Boyce

Bone Research2024，Vol.12Issue(3)：P.734-744,11.
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Bone Research2024，Vol.12Issue(3)：P.734-744,11.DOI:10.1038/s41413-024-00352-6

Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects

Zhenqiang Yao 1Akram Ayoub 1Venkatesan Srinivasan 2Jun Wu 1Churou Tang 3Rong Duan 1Aleksa Milosavljevic 2Lianping Xing 1Frank H.Ebetino 4Alison J.Frontier 2Brendan F.Boyce1

作者信息

  • 1. Department of Pathology and Laboratory Medicine,University of Rochester Medical Center,Rochester,NY 14642,USA
  • 2. Department of Chemistry,University of Rochester,Rochester NY14627,USA
  • 3. Department of Pathology and Laboratory Medicine,University of Rochester Medical Center,Rochester,NY 14642,USA School of Arts and Sciences,University of Rochester,Rochester NY14627,USA
  • 4. Department of Chemistry,University of Rochester,Rochester NY14627,USA BioVinc,LLC,Pasadena,CA 91107,USA
  • 折叠

摘要

关键词

res/conjugate/phosphonate

分类

医药卫生

引用本文复制引用

Zhenqiang Yao,Akram Ayoub,Venkatesan Srinivasan,Jun Wu,Churou Tang,Rong Duan,Aleksa Milosavljevic,Lianping Xing,Frank H.Ebetino,Alison J.Frontier,Brendan F.Boyce..Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects[J].Bone Research,2024,12(3):P.734-744,11.

基金项目

funded by National Institutes of Health,National Institute on Aging,grant numbers,R01AG076731,R01AG049994 （）

National Institute for Arthritis and Musculoskeletal and Skin Diseases,R01AR043510,and P30 AR069655。 （）

Bone Research

OAMEDLINE

2095-4700

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