中医康复2024，Vol.1Issue(12)：1-6,6.DOI:10.19787/j.issn.2097-3128.2024.12.001
中医康复疗法对中老年人膝骨性关节炎的多中心随机对照试验
Multi-Center Randomized Controlled Trial on Traditional Chinese Medicine Rehabilitation Therapy for Knee Osteoarthritis in Middle-Aged and Elderly Patients
摘要
Abstract
Objective:To explore the clinical efficacy and safety of Traditional Chinese Medicine Rehabilitation therapy on knee osteoarthritis and provide scientific basis for the formulation of TCM evidence-based clinical practice guidelines.Methods:Multicenter,prospective,randomized con-trolled clinical trial were used.A total of 157 patients with KOA were included from three centers in this study.Using a central randomization system,patients will be randomized(1:1)into groups receiving either traditional Chinese medicine rehabilitation therapy or physical therapy.The Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC),visual analog scale(VAS),knee outcome survey activities of daily living scale(KOS-ADLS)and time up and go test(TUG),were used to evaluate knee pain,balance and functional status while recording adverse events.All pa-tients were evaluated at baseline,after the last treatment,and at the 1-month follow-up period.Results:There were 143 effective cases,71 in the treat-ment group and 72 in the control group.Compared with before treatment in the same group,WOMAC score,VAS score,KOS-ADLS score and TUG in both groups were improved significantly after last treatment and at the last follow-up(P<0.001).After the last treatment,the WOMAC score,VAS score,KOS-ADLS score,and TUG of the two groups were similar(P>0.05).At the last follow-up,the VAS scores were significant difference be-tween the two groups(P<0.05),the WOMAC score and KOS-ADLS score was similar(P>0.05).There was no significantly difference in the safety(P>0.05).Conclusions:Traditional Chinese Medicine Rehabilitation therapy is safe and effective in the treatment of KOA,as effective as physical therapy,which can integrate the functions of knee stepping,balancing and weight-bearing.It can be used as the first-line of treatment for KOA.In ad-dition,it is more in line with the current trend of healthcare integration in China,which is conducive to patients'self-rehabilitation and may be more advantageous in relieving knee pain and restoring the best functional status of the lower limbs.关键词
膝骨性关节炎/中医康复疗法/针刺/推拿/南少林站桩功/多中心随机对照临床研究试验Key words
knee osteoarthritis/traditional Chinese medicine rehabilitation therapy/acupuncture/Tuina/southern Shaolin standing stake exercise/multi-center randomized controlled trial分类
医药卫生引用本文复制引用
陈晓琴,仲卫红,叶佳佳,李宇涛,王缤毅,杨珊莉..中医康复疗法对中老年人膝骨性关节炎的多中心随机对照试验[J].中医康复,2024,1(12):1-6,6.基金项目
福建省科技计划项目(2021Y4017) （2021Y4017）
福建省康复技术重点试验室开放课题(XKF2023001) （XKF2023001）
福建中医药大学中医骨伤科学学科开放课题(XGS2023007) （XGS2023007）
