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中药复方多糖对肉鸡生长性能、免疫调节及肠道菌群的影响

刘思莹 杨侃侃 苏顺达 李逸飞 毕艺萌 叶力维 李敬双 于洋

饲料研究2024,Vol.47Issue(19):59-64,6.
饲料研究2024,Vol.47Issue(19):59-64,6.DOI:10.13557/j.cnki.issn1002-2813.2024.19.012

中药复方多糖对肉鸡生长性能、免疫调节及肠道菌群的影响

Effects of traditional Chinese medicine compound polysaccharides on growth performance,immune regulation,and intestinal flora of broilers

刘思莹 1杨侃侃 2苏顺达 1李逸飞 1毕艺萌 1叶力维 1李敬双 1于洋1

作者信息

  • 1. 锦州医科大学,辽宁锦州 121001
  • 2. 辽宁省农业经济学校,辽宁锦州 121001
  • 折叠

摘要

Abstract

The experiment aimed to study the impact of traditional Chinese medicine compound polysaccharides on the growth performance,immune moderation,and intestinal flora of broilers.A total of 900 1-day-old broilers were selected.The broilers in the blank control group(BCG)were fed a basal diet,and those in the positive control group(PCG)were fed a basal diet supplemented with 10 mg/kg levamisole hydrochloride,and those in different concentrations of TCMCP groups(0.5%,1.0%,and 2.0%TCMCPG)were fed a basal diet supplemented with 0.5%,1.0%,and 2.0%TCMCP.There were 3 replicates in each group and 60 broilers in each replicate.The experiment lasted for 42 days.The results showed that the final weight of 0.5%,1.0%,and 2.0%TCMCPG groups was extremely higher than the BCG group(P<0.01).1.0%TCMCPG group extremely increased average daily gain(P<0.01),0.5%and 2.0%TCMCPG groups significantly increased average daily gain(P<0.05).The ratio of feed to gain in 0.5%,1.0%and 2.0%TCMCPG groups was extremely decreased(P<0.01).Serum immunoglobulin G(IgG)content in 1.0%and 2.0%TCMCPG groups was extremely higher than the BCG group(P<0.0l),and serum IgG content in 0.5%TCMCPG group was significantly increased(P<0.05).1.0%TCMCPG group extremely increased the content of immunoglobulin A(IgA)(P<0.01).Serum immunoglobulin M(IgM)content in 1.0%and 2.0%TCMCPG groups was significantly increased(P<0.05).In 0.5%,1.0%and 2.0%TCMCPG groups,thymus,bursa,and spleen indexes were extremely increased(P<0.01),and serum concentrations of interleukin-2(IL-2),interleukin-4(IL-4),and interferon-y(IFN-γ)were extremely increased(P<0.01).The number and volume of lymphocytes in the splenic tissue structure increased.In terms of intestinal flora,0.5%,1.0%and 2.0%TCMCPG groups extremely decreased the number of Escherichia coli in jejunum and cecum(P<0.01),and extremely increased the number of Lactobacillus in cecum(P<0.01).The Lactobacillus number in jejunum was extremely increased in 1.0%TCMCPG group(P<0.0l).The study indicates that TCMCP can improve the immune function,improve the enteric microbiome,and improve growth performance,1.0%TCMCPG has the best effect.

关键词

中药复方多糖/肉仔鸡/生长性能/免疫功能/肠道菌群

Key words

traditional Chinese medicine compound polysaccharide/broilers/growth performance/immune function/intestinal flora

分类

农业科技

引用本文复制引用

刘思莹,杨侃侃,苏顺达,李逸飞,毕艺萌,叶力维,李敬双,于洋..中药复方多糖对肉鸡生长性能、免疫调节及肠道菌群的影响[J].饲料研究,2024,47(19):59-64,6.

基金项目

2023年大学生创新创业计划训练项目(项目编号:S202310160010) (项目编号:S202310160010)

2022年度辽宁省教育厅重点攻关项目(项目编号:LJKZZ20220094) (项目编号:LJKZZ20220094)

饲料研究

OA北大核心CSTPCD

1002-2813

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