饲料研究2024,Vol.47Issue(19):59-64,6.DOI:10.13557/j.cnki.issn1002-2813.2024.19.012
中药复方多糖对肉鸡生长性能、免疫调节及肠道菌群的影响
Effects of traditional Chinese medicine compound polysaccharides on growth performance,immune regulation,and intestinal flora of broilers
摘要
Abstract
The experiment aimed to study the impact of traditional Chinese medicine compound polysaccharides on the growth performance,immune moderation,and intestinal flora of broilers.A total of 900 1-day-old broilers were selected.The broilers in the blank control group(BCG)were fed a basal diet,and those in the positive control group(PCG)were fed a basal diet supplemented with 10 mg/kg levamisole hydrochloride,and those in different concentrations of TCMCP groups(0.5%,1.0%,and 2.0%TCMCPG)were fed a basal diet supplemented with 0.5%,1.0%,and 2.0%TCMCP.There were 3 replicates in each group and 60 broilers in each replicate.The experiment lasted for 42 days.The results showed that the final weight of 0.5%,1.0%,and 2.0%TCMCPG groups was extremely higher than the BCG group(P<0.01).1.0%TCMCPG group extremely increased average daily gain(P<0.01),0.5%and 2.0%TCMCPG groups significantly increased average daily gain(P<0.05).The ratio of feed to gain in 0.5%,1.0%and 2.0%TCMCPG groups was extremely decreased(P<0.01).Serum immunoglobulin G(IgG)content in 1.0%and 2.0%TCMCPG groups was extremely higher than the BCG group(P<0.0l),and serum IgG content in 0.5%TCMCPG group was significantly increased(P<0.05).1.0%TCMCPG group extremely increased the content of immunoglobulin A(IgA)(P<0.01).Serum immunoglobulin M(IgM)content in 1.0%and 2.0%TCMCPG groups was significantly increased(P<0.05).In 0.5%,1.0%and 2.0%TCMCPG groups,thymus,bursa,and spleen indexes were extremely increased(P<0.01),and serum concentrations of interleukin-2(IL-2),interleukin-4(IL-4),and interferon-y(IFN-γ)were extremely increased(P<0.01).The number and volume of lymphocytes in the splenic tissue structure increased.In terms of intestinal flora,0.5%,1.0%and 2.0%TCMCPG groups extremely decreased the number of Escherichia coli in jejunum and cecum(P<0.01),and extremely increased the number of Lactobacillus in cecum(P<0.01).The Lactobacillus number in jejunum was extremely increased in 1.0%TCMCPG group(P<0.0l).The study indicates that TCMCP can improve the immune function,improve the enteric microbiome,and improve growth performance,1.0%TCMCPG has the best effect.关键词
中药复方多糖/肉仔鸡/生长性能/免疫功能/肠道菌群Key words
traditional Chinese medicine compound polysaccharide/broilers/growth performance/immune function/intestinal flora分类
农业科技引用本文复制引用
刘思莹,杨侃侃,苏顺达,李逸飞,毕艺萌,叶力维,李敬双,于洋..中药复方多糖对肉鸡生长性能、免疫调节及肠道菌群的影响[J].饲料研究,2024,47(19):59-64,6.基金项目
2023年大学生创新创业计划训练项目(项目编号:S202310160010) (项目编号:S202310160010)
2022年度辽宁省教育厅重点攻关项目(项目编号:LJKZZ20220094) (项目编号:LJKZZ20220094)