武警医学2024，Vol.35Issue(10)：829-832,4.
采用参附注射液治疗脓毒症对相关临床指标的影响
Effect of Shenfu injection on relevant indicators in patients with sepsis
何华亮 1刘晶晶 1王芬 2李涛 1王书升 1徐虹 1琚会军1
作者信息
- 1. 100027,武警北京总队医院急诊医学科
- 2. 100029,北京中医药大学第三附属医院内分泌科
- 折叠
摘要
Abstract
Objective To observe the effect of Shenfu injection on relevant indicators in patients with sepsis.Methods A to-tal of 60 patients with severe sepsis admitted after treatment into the Emergency Medicine Department of a Grade-A hospital in Beijing from October 2017 to October 2021 were selected as the study objects and randomly divided into observation group and control group,with 30 cases in each group.Patients in both groups were given conventional treatment measures such as fluid replenishment,expan-sion and anti-infection according to the guidelines.Observation group was given intravenous infusion of Shenfu injection on the basis of standard treatment,once a day,7 days as a course of treatment,a total of two courses of treatment.The changes of serum CRP and PCT before treatment and during hospitalization of the two groups were observed,and the APACHEⅡ score and length of hospitaliza-tion during treatment were compared and analyzed.Results On the 3rd,7th,10th and 14th day of Shenfu injection treatment,A-PACHEⅡ score,SOFA score,serum CRP and PCT concentration in observation group were significantly lower than those in control group,with statistical significance(P<0.05).The total hospitalization time of observation group was(16.23±2.74)d,which was significantly shorter than that of control group[(21.67±3.52)d],and the difference was statistically significant(P<0.05).Conclusions The treatment of sepsis with Shenfu injection can improve the relevant indexes,and the clinical effect is remarkable.关键词
降钙素原/C-反应蛋白/参附注射液/脓毒症Key words
procalcitionin/C-reactive protein/Shenfu injection/sepsis分类
医药卫生引用本文复制引用
何华亮,刘晶晶,王芬,李涛,王书升,徐虹,琚会军..采用参附注射液治疗脓毒症对相关临床指标的影响[J].武警医学,2024,35(10):829-832,4.
