儿童重症监护病房与呼吸机相关的肺炎危险因素Meta分析OACSTPCD

Objective To systematically evaluate the risk factors for ventilator-associated pneumonia(VAP)in pediatric in-tensive care units(PICU).Methods Chinese and English databases such as CNKI,VIP,Wanfang,PubMed,Embase,The Co-chrane Library,and CBM,were searched for literature on VAP risk factors in PICU.Meta-analysis was performed using RevMan5.4 and stata15.0.Results A total of 14 articles were included,including 9 in Chinese and 5 in English,involving 5,242 patients.Thir-teen potential risk factors were comprehensively evaluated,and subgroup analysis were performed based on the study area.The results showed that age<1 year,respiratory disease,repeated intubation,parenteral nutrition,bronchoscopy,use of glucocorticoids,sedatives and acid suppressants were risk factors for VAP in PICU(P<0.05).Subgroup analysis indicated that these factors were statistically significant across different regions of China(P<0.05).Conclusions Medical staff should closely monitor the identified risk factors,utilize early detection strategies,and implement effective preventive measures to reduce the occurrence of VAP in PICU.