分子影像学杂志2024，Vol.47Issue(11)：1155-1162,8.DOI:10.12122/j.issn.1674-4500.2024.11.01
右室量化分析系统联合心肌损伤标志物可指导脓毒性休克患者的预后
Right ventricular quantitative analysis system combined with myocardial injury markers can guide the prognosis of patients with septic shock
摘要
Abstract
Objective To investigate the prognostic value of right ventricular quantitative analysis system(RVQAS)combined with myocardial injury markers in patients with septic shock.Methods A total of 100 patients with septic shock admitted to the Department of Critical Care Medicine of the First Affiliated Hospital of Bengbu Medical University from May 2018 to May 2023 were selected and divided into survival group(n=76)and death group(n=24)according to the prognosis after 28 days,Quantitative medical parameters of the right ventricle of patients were recorded by RVQAS using bedside ultrasound.At the same time,the serum concentrations of myocardial injury markers on the day of admission were collected,and the above results were included in the statistical analysis.Results Right ventricular end-diastolic volume(RVEDV),Right ventricular end-diastolic volume index(RVEDVI),Right ventricular end-systolic volume(RVESV)and Right ventricular end-systolic volume index(RVESVI)in the death group were higher than those in the survival group(P<0.05).right ventricular ejection fraction(RVEF),right ventricular cardiac output,right ventricular cardiac index,right ventricular stroke volume and right ventricular stroke volume index were lower in the death group than in the survival group(P<0.05).The serum concentrations of creatine kinase(CK),creatine kinase isoenzyme and cardiac troponin I(cTnI)in the death group were higher than those in the survival group(P<0.05).Spearman correlation analysis showed that the death of patients was positively correlated with RVEDV,RVEDVI,RVESV,RVESVI,CK and cTnI,and negatively correlated with RVEF(P<0.05).The ROC curve showed that the area under the curve of RVESVI alone was 0.948,and the area under the curve of RVESVI combined with CK was 0.999 in the diagnosis of septic shock,and the predictive value of RVESVI for death was the highest.Conclusion RVQAS measurement of right ventricular function can provide more reference information for the timely and effective treatment of patients with septic shock.RVESVI combined with CK has the highest predictive value for the death of patients,and should be used in clinical practice earlier to bring greater benefits for the early diagnosis and treatment of patients.关键词
右室量化分析系统/心肌标志物/脓毒性休克Key words
right ventricular quantitative analysis system/myocardial markers/septic shock引用本文复制引用
张懿瑶,牛凯旋,吕宏安,赵士兵..右室量化分析系统联合心肌损伤标志物可指导脓毒性休克患者的预后[J].分子影像学杂志,2024,47(11):1155-1162,8.基金项目
安徽省教育厅自然科学重点项目(KJ2021A0735) （KJ2021A0735）
