赣南医科大学学报2024，Vol.44Issue(10)：1023-1029,7.DOI:10.3969/j.issn.1001-5779.2024.10.009
定量脑电图与病毒性脑炎预后的相关分析
Correlation analysis between quantitative electroencephalography and prognosis of viral encephalitis
摘要
Abstract
Objective:To analyse the value of quantitative electroencephalography(QEEG)in adult viral encephalitis(VE)and to clarify its predictive effect on prognosis.Methods:A total of 35 VE patients admitted to the department of neurology of Ganzhou People's Hospital(meeting the inclusion criteria)from September 2021 to September 2023 and meeting the inclusion criteria were collected.Critical(16 cases)and non-critical(19 cases)groups were categorised according to whether they were admitted to the ICU or not,and the 3-month modified Rankin Scale(mRS)was used to assess outcomes,mRS score≤2,favorable prognosis;mRS score≥3,unfavorable prognosis.Within 24 hours of hospital admission,all patients received at least 2 hours of EEG with QEEG power spectral analysis.The brain was divided into 5 regions,frontal(F),central(C),temporal(T),parietal(P)and occipital(O),the QEEG data included the δ/α value(DAR),δ+θ/α+β value(DTABR),by statistically analysing whether there was any difference in QEEG data between the critically ill and non-critically ill groups,and between the good prognosis and poor prognosis groups.Results:The values of FDAR,PDTABR and PDAR were higher in the critical group than those in the non-critical group,the difference was statistically significant(P＜0.05).After adjusting for the presence or absence of pneumonia,time from onset to admission,and length of hospitalisation,with FDAR,PDTABR and PDAR as independent variables and whether or not the patient was critically ill as the dependent variable,respectively,no QEEG data were found to be an independent predictor of disease severity.There were 28 cases(88％)in the good prognosis group and 7 cases(20％)in the poor prognosis group,and the poor prognosis group had higher FDAR,TDAR,TDTABR,CD AR,CDTABR,PDAR,PDTABR,ODAR and ODTABR values,the differences were statistically significant(P＜0.05)when comparing between the groups.Using the QEEG data that differed between the two groups as the independent variable and the long-term prognosis as the dependent variable,respectively,after adjusting for whether or not they were admitted to the ICU,length of hospital stay and cerebrospinal fluid IL-6,it was found that CDAR and CDTABR could be used as independent predictors of prognosis,and CDAR had the highest predictive value of prognosis,with a cutoff value of 7.9.Conclusion:QEEG can be an important tool for assessing the prognosis of patients with VE,and patients with severe disease and poor prognosis have a higher degree of slow-wave component.关键词
定量脑电图/病毒性脑炎/预后Key words
Quantitative electroencephalography/Viral encephalitis/Prognosis分类
医药卫生引用本文复制引用
王聪,袁旭娟,江宗华..定量脑电图与病毒性脑炎预后的相关分析[J].赣南医科大学学报,2024,44(10):1023-1029,7.基金项目
江西省卫生健康委员会科技计划项目(202212477) （202212477）
