实用临床医药杂志2024，Vol.28Issue(20)：72-76,5.DOI:10.7619/jcmp.20233970
妊娠晚期孕妇发生睡眠障碍的危险因素分析及预测模型的构建
Analysis of risk factors for sleep disorders in pregnant women in the third trimester and establishment of prediction model
摘要
Abstract
Objective To explore the risk factors for sleep disorders in late pregnancy pregnant women,and establish predictive nomogram.Methods A total of 319 pregnant women in late preg-nancy were selected,and were divided into sleep disorder group(n=131)and non-sleep disorder group(n=188)based on whether they experienced sleep disorders in late pregnancy.Logistic re-gression analysis was applied to screen for risk factors of sleep disorders in late pregnancy pregnant women;R software was applied to establish a nomogram for predicting sleep disorders in late pregnan-cy pregnant women.Receiver operating characteristic(ROC)curve,calibration curve and Hosmer-Lemeshow goodness of fit test were used to evaluate the efficacy of the nomogram in predicting sleep disorders in third trimester pregnant women.Results Out of 319 late pregnancy pregnant women,131 had sleep disorders,accounting for 41.07％.Logistic regression analysis showed that history of spontaneous abortion(95％CI,2.120 to 8.703,P＜0.001),anxiety(95％CI,1.644 to 5.313,P＜0.001),depression(95％CI,2.169 to 7.477,P＜0.001),alcohol consumption in the first six months of pregnancy(95％CI,1.690 to 5.828,P＜0.001),pregnancy complications or complica-tions(95％CI,1.610 to 4.851,P＜0.001),video time at bed before sleep＞0.5 h(95％CI,1.069 to 3.192,P=0.028)were independent risk factors for sleep disorders in third trimester pregnant women.The area under the ROC curve was 0.788(95％CI,0.739 to 0.838).The slope of the calibration curve was close to 1,and the Hosmer-Lemeshow goodness of fit test showed a better re-sults(x2=6.055,P=0.417).Conclusion Pregnant women in late pregnancy have a higher in-cidence of sleep disorders.Patients with a history of natural abortion,anxiety,depression,drinking alcohol within six months before pregnancy,pregnancy comorbidities or complications,and video time＞0.5 h at bed before sleep are independent risk factors.The nomogram model based on these 6 independent risk factors can help predict the occurrence of sleep disorders in pregnant women in the third trimester.关键词
妊娠晚期/孕妇/睡眠障碍/危险因素/列线图Key words
late pregnancy/pregnant women/sleep disorders/risk factors/nomogram分类
医药卫生引用本文复制引用
赵雪,周银,李明..妊娠晚期孕妇发生睡眠障碍的危险因素分析及预测模型的构建[J].实用临床医药杂志,2024,28(20):72-76,5.基金项目
江苏省妇幼健康科研项目(F202029) （F202029）
