实用临床医药杂志2024，Vol.28Issue(20)：77-81,5.DOI:10.7619/jcmp.20242374
回收式自体输血在高出血风险产妇剖宫产术中的应用研究
Application of recovered autologous blood transfusion in cesarean section for puerperas with high risk of hemorrhage
摘要
Abstract
Objective To investigate the clinical application of recovered autologous blood trans-fusion in cesarean section for puerperas with high risk of hemorrhage.Methods A total of 100 puer-peras with cesarean section were selected,and they were preoperatively diagnosed with high-risk hem-orrhage,including perilous placenta previa,placenta accreta,placental abruption,threatened uterine rupture,and scarred uterus.According to the different blood transfusion methods,50 puerperas re-ceiving autologous blood transfusion were assigned to observation group,and 50 puerperas receiving allogeneic blood transfusion were assigned to control group.Clinical indicators,blood routine tests,coagulation function,inflammatory factors,and postoperative adverse reactions were compared be-tween the two groups.Results The intraoperative blood loss,intraoperative blood transfusion vol-ume,blood costs,total costs,operative duration,and hospitalization time in the observation group were significantly shorter or lower than those in the control group.Immediately after blood transfusion(T1),there were no significant differences in blood routine indicators between the two groups(P＞0.05).At the end of blood transfusion(T2)and 24 hours after surgery(T3),there was no signifi-cant difference in hematocrit(Hct)between the two groups(P＞0.05),while the hemoglobin(Hb)and platelet(Plt)levels in the observation group were significantly higher than those in the control group(P＜0.05).At T1,there were no significant differences in coagulation function indicators between the two groups(P＞0.05).At T2 and T3,there were no significant differences in D-dimer(D-D)between the two groups(P＞0.05),while the prothrombin time(PT),thrombin time(TT),and activated partial thromboplastin time(APTT)in the observation group were significantly shorter than those in the control group,and fibrinogen(Fib)was significantly higher in the observationgroup(P＜0.05).At 48 hours after blood transfusion,the serum procalcitonin(PCT)and interleukin-6(IL-6)levels in the observation group were significantly lower than those in the control group(P＜0.05).The number of cases with allergic reactions,infections,and hypotension in the observation group was significantly lower than that in the control group,but there was no significant difference in the total incidence rate of adverse reactions between the two groups(P＞0.05).Conclusion Clin-ical application of recovered autologous blood transfusion in cesarean section for puerperas with high risk of hemorrhage shows remarkable effects.关键词
回收式自体输血/高出血风险产妇/剖宫产术/血常规/凝血功能/炎症因子Key words
recovered autologous blood transfusion/puerperas with high risk of hemorrhage/cesarean section/blood routine/coagulation function/inflammatory factors分类
医药卫生引用本文复制引用
单家媛,罗玲,马燕,秦旭..回收式自体输血在高出血风险产妇剖宫产术中的应用研究[J].实用临床医药杂志,2024,28(20):77-81,5.基金项目
四川省医学会医学(青年创新)科研课题(S22096) （青年创新）
