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厚朴酚对断奶羔羊生长性能、免疫功能和抗氧化功能的影响

刘学贤 岳伟东 郭春燕

饲料研究2024,Vol.47Issue(20):23-26,4.
饲料研究2024,Vol.47Issue(20):23-26,4.DOI:10.13557/j.cnki.issn1002-2813.2024.20.005

厚朴酚对断奶羔羊生长性能、免疫功能和抗氧化功能的影响

Effects of magnolol on growth performance,immune function,and antioxidant capacity of weaned lambs

刘学贤 1岳伟东 2郭春燕3

作者信息

  • 1. 晋中职业技术学院生物工程系,山西晋中 030600
  • 2. 北京科牧丰生物制药有限公司,北京 102600
  • 3. 中国农业大学动物医学院,北京 100193
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摘要

Abstract

The experiment aimed to investigate the effects of magnolol on the growth performance,immune function,and antioxidant capacity of weaned lambs.A total of 32 weaned Hu sheep lambs were randomly divided into four groups,with eight replicates per group and one lamb per replicate.The control group was fed a basal diet,while the experimental groups were fed experimental diets containing 0.05%,0.10%,and 0.20%magnolol,respectively.The pretrial period was one week,and the formal trial period was 60 days.The results showed that the total weight gain and average daily weight gain in the 0.10%magnolol group increased by 30.90%and 30.98%compared to the control group(P<0.05),respectively.The feed conversion ratio in the 0.10%and 0.20%magnolol groups decreased by 19.67%and 12.31%compared to the control group(P<0.05),respectively.The diarrhea rates in the 0.05%,0.10%,and 0.20%magnolol groups decreased by 37.53%,75.06%,and 52.97%compared to the control group(P<0.05),respectively.Compared to the control group,the levels of serum immunoglobulin A(IgA)and immunoglobulin G(IgG)in the 0.10%magnolol group were significantly increased(P<0.05).The serum interleukin-4(IL-4)level in the 0.10%magnolol group was significantly increased(P<0.05),while the serum interleukin-6(IL-6)level in the 0.10%and 0.20%magnolol groups was significantly decreased(P<0.05).The serum interleukin-10(IL-10)level in the 0.10%magnolol group was significantly increased(P<0.05),and the tumor necrosis factor-alpha(TNF-α)level was significantly decreased(P<0.05).The serum interferon-γ(IFN-γ)level in the 0.05%,0.10%and 0.20%magnolol groups was significantly increased(P<0.05).The activities of total superoxide dismutase(T-SOD)and total antioxidant capacity(T-AOC)in the serum of the 0.10%and 0.20%magnolol groups were significantly increased(P<0.05),while the level of malondialdehyde(MDA)in the serum of the 0.05%,0.10%,and 0.20%magnolol groups was significantly decreased(P<0.05).The study indicates that the addition of magnolol to the diet of Hu sheep lambs can improve growth performance,reduce diarrhea rates,enhance immunity,and increase antioxidant capacity.The appropriate addition level of magnolol is 0.10%.

关键词

厚朴酚/断奶羔羊/生长性能/腹泻率/免疫功能/抗氧化功能

Key words

magnolol/weaned lambs/growth performance/diarrhea rate/immune function/antioxidant capacity

分类

农业科技

引用本文复制引用

刘学贤,岳伟东,郭春燕..厚朴酚对断奶羔羊生长性能、免疫功能和抗氧化功能的影响[J].饲料研究,2024,47(20):23-26,4.

基金项目

山西省基础研究计划(项目编号:20210302124338) (项目编号:20210302124338)

饲料研究

OA北大核心CSTPCD

1002-2813

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