实用休克杂志（中英文）2024，Vol.8Issue(3)：152-155,4.
集束化诊疗对G6PD缺乏急性感染重症患儿的疗效研究
Study on the efficacy of bundled in critically Ⅲ children with acute infections and G6PD deficiency
摘要
Abstract
Objective To evaluate the efficacy of bundled management strategies in children with acute infections and G6PD deficiency.Methods The clinical data of 120 uremia patients who re-ceived Qualcomm hemodialysis in our hospital from October 2022 to October 2023 were collected and analyzed retrospectively.Logistic regression was used to analyze the independent risk factors of CRBSI in uremic Qualcomm hemodialysis patients,and the ROC curve was drawn to evaluate the prediction effect of the model.Results There were no significant differences in serum IL-6 and CRP levels at ad-mission between the two groups.After 24 hours of bundled preventive strategies,the observation group had significantly lower serum IL-6 and CRP levels compared to the control group(P＜0.05).The incidence rates of sepsis(68.75％vs.82.50％),septic shock(47.50％vs.63.75％),MODS(57.50％vs.73.75％),and mortality rate(7.50％vs.18.75％)were significantly lower in the obser-vation group,while the cure and improvement rate was significantly higher(92.50％vs.81.25％)compared to the control group(P＜0.05).The observation group also had a significantly shorter PICU stay(6.11±5.06 daysvs.7.98±6.55 days)and lower hospitalization costs(31 908.57±11203.92 RMBvs.35 319.33±10 312.63 RMB)compared to the control group(P＜0.05).Conclusions Bundled management strategies effectively reduce the inflammatory response in critically ill children with G6PD deficiency and acute infections,decrease the incidence of sepsis and its complications,im-prove prognosis,shorten hospitalization time,and reduce treatment costs.These strategies are wor-thy of clinical promotion and application.关键词
集束化诊疗管理策略/G6PD缺乏/急性感染/重症患儿/疗效研究Key words
Bundled management strategies/G6PD deficiency/Acute infections/Critically Ⅲ children/Efficacy study引用本文复制引用
韦海娟,郑劫,唐育鹏,韦蓉,莫武桂..集束化诊疗对G6PD缺乏急性感染重症患儿的疗效研究[J].实用休克杂志（中英文）,2024,8(3):152-155,4.基金项目
广西医疗卫生适宜技术与开发课题(项目编号:S201405-04) （项目编号:S201405-04）
广西儿科疾病临床医学研究中心项目(项目编号:桂科AD22035121) （项目编号:桂科AD22035121）
