单胎妊娠胎儿生长受限的危险因素及其对胎儿结局的影响OACSTPCD

Objective To explore the risk factors of fetal growth restriction(FGR)in single pregnancy and its influence on fe-tal outcomes.Methods The clinical data of 375 single pregnancies with FGR admitted to the First Medical Center of PLA General Hospital from January 2018 to December 2022 were retrospectively analyzed and set as the study group,and 375 clinical data of single pregnancies without FGR were also collected through stratified sampling and set as the control group.Maternal factors,fetal accessory factors,delivery modes and fetal outcomes were compared between the two groups,the risk factors of FGR were explored by multivari-ate logistic regression analysis,and the fetal outcomes of FGR were analyzed.Results Placenta abnormities[OR(95%CI):6.259(3.263-12.004)],umbilical cord abnormities[7.500(3.034-18.542)],amniotic fluid abnormities[6.366(1.050-38.606)],decreased placental area[0.989(0.986-0.992)],hypertension[4.100(2.087-8.055)],anemia[2.387(1.271-4.485)]and increased maternal BMI[1.076(1.020-1.135)]were independent risk factors for FGR,and the greater the delivery week[0.842(0.728-0.975)],the lower the probability of FGR.The rate of preterm delivery(26.7%),cesarean section(49.6%),fetal dis-tress(18.1%)and fetal mortality(2.9%)in the study group were significantly higher than those in the control group(1.3%,35.5%,5.1%,0%;P<0.05).Conclusions The risk factors for FGR are numerous and interactive which increases the risk of ad-verse fetal outcomes.Early screening of FGR,monitoring during pregnancy,prevention and treatment of pregnancy complications dur-ing pregnancy should be strengthened to improve maternal and fetal outcomes.