陕西科技大学学报2024，Vol.42Issue(6)：96-104,111,10.
基于纳米四氧化三铁改性的电化学传感器的构建及用于色氨酸检测的研究
Study on construction of electrochemical sensors based on modified iron tetraoxide nanoparticles and their use for tryptophan detection
摘要
Abstract
L-tryptophan is the most important amino acid in the human body and plays a key role in human growth and development.In this study,a highly sensitive electrochemical sen-sor was prepared by modifying ferroferric oxide nanomaterials(Fe3O4 NMs)on the surface of carbon cloth(CC)for the detection of L-tryptophan samples.The introduction of Fe3O4 NMs provided the sensor with a large electrochemical area and high electrocatalytic perform-ance,and the detection sensitivity was significantly improved due to the increase of electrode channels for the mass transfer process.The current peaks measured via differential pulse vol-tammetry(DPV)were linearly related to a variety of concentrations of L-tryptophan.Under the optimal conditions,the limit of detection(LOD)of this homemade sensor was as low as 1.68 μM for L-tryptophan,and the linear concentration range was 5～200 μM,with an in-crease in sensitivity of 1.01 mA/M·cm2.In addition,the Fe3O4 NMs/CC-based sensor showed good accuracy and stability in actual sample detection like serum and urine,indica-ting that the system possesses the potential to be a point-of-care testing.关键词
电化学传感器/Fe3O4 NMs/CC/色氨酸/灵敏度Key words
electrochemical sensor/Fe3O4 NMs/CC/L-tryptophan/sensitivity分类
化学化工引用本文复制引用
李翔宇,杨冬,李旭华,张婷,陈际帆,姚团利..基于纳米四氧化三铁改性的电化学传感器的构建及用于色氨酸检测的研究[J].陕西科技大学学报,2024,42(6):96-104,111,10.基金项目
陕西省科技厅重点研发计划项目(2022NY-042) （2022NY-042）
陕西省西安市科技局高校院所科技人员服务企业项目(22GXFW0012) （22GXFW0012）
陕西科技大学博士科研启动基金项目(BJ15-17) （BJ15-17）
