岩矿测试2025，Vol.44Issue(1)：140-148,9.DOI:10.15898/j.ykcs.202407020145
生物样品中汞的电感耦合等离子体质谱分析与干扰校正方法
Inductively Coupled Plasma-Mass Spectrometric Analysis of Mercury in Biological Samples and Interference Correction Methods
摘要
Abstract
It is difficult to directly and accurately determine Hg in biological samples using inductively coupled plasma-mass spectrometry(ICP-MS)due to polyatomic interferences,such as tungsten oxide,and matrix effects.We established an ICP-MS method for the determination of Hg in biological samples based on the kinetic energy discrimination(KED)mode combined with mathematical correction and internal standard correction.In this experiment,spectral interferences of Hg in standard(STD)mode and KED mode were investigated.202Hg was selected as the analyzed isotope in the KED mode,effectively reducing but not completely eliminating the interference.It was found that the interference amount of W with Hg was linearly related to the concentration of W(R2=0.9997).The matrix interference was eliminated with internal standard(Rh concentration of 50μg/L)and sample dilution(dilution of 100 times).The reliability of the method was tested with 9 reference materials,and the results were in agreement with certified values(or reference values).In particular,the accuracy of GBW10028(Astragalus membranaceus),GBW10025(spirulina)and GBW10015a(spinach)was significantly improved.The relative standard deviation(n=10)was 0.7%to 7.0%.The method is suitable for the analysis of Hg in biological samples.关键词
生物样品/汞/电感耦合等离子体质谱法/干扰校正Key words
biological sample/mercury/inductively coupled plasma-mass spectrometry/interference correction分类
化学化工引用本文复制引用
张灵火,马娜,陈海杰,张鹏鹏,胡梦颖,徐进力,白金峰..生物样品中汞的电感耦合等离子体质谱分析与干扰校正方法[J].岩矿测试,2025,44(1):140-148,9.基金项目
国家重点研发计划项目(2021YFC2903001) （2021YFC2903001）
中国地质调查局地质调查项目(DD20221770) （DD20221770）
