临床医学工程2024,Vol.31Issue(11):1357-1358,2.DOI:10.3969/j.issn.1674-4659.2024.11.1357
喹硫平联合坦度螺酮治疗精神分裂症的效果
Effect of Quetiapine Combined with Tandospirone in the Treatment of Schizophrenia
周峰 1王爱梅 1王幼钦 1张兆麟 1冯丽1
作者信息
- 1. 福州市精神病人疗养院精神科,福建 福州 350008
- 折叠
摘要
Abstract
Objective To explore the effect of quetiapine combined with tandospirone in the treatment of patients with schizophrenia.Methods 150 patients with schizophrenia admitted to our hospital from April 2020 to March 2023 were randomly divided into observation group and control group.The control group was treated with quetiapine,and the observation group was treated with quetiapine combined with tandospirone.The psychiatric symptoms,cognitive function and adverse reactions were compared between two groups.Results After treatment,the PANSS scores of the two groups decreased,and the PANSS scores of the observation group were lower than those of the control group(P<0.05).After treatment,the LOTCA scores of the two groups increased,and the LOTCA score of the observation group was higher than that of the control group(P<0.05).The incidence of adverse reactions in the observation group was 14.67%,which had no statistical difference with 12.00%in the control group(P>0.05).Conclusions Quetiapine combined with tandospirone in the treatment of patients with schizophrenia can relieve the symptoms,and improve the cognitive function of patients,with higher safety.关键词
喹硫平/坦度螺酮/精神分裂症Key words
Quetiapine/Tandospirone/Schizophrenia分类
医药卫生引用本文复制引用
周峰,王爱梅,王幼钦,张兆麟,冯丽..喹硫平联合坦度螺酮治疗精神分裂症的效果[J].临床医学工程,2024,31(11):1357-1358,2.