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电针对慢性失眠症患者脑电特征信号的影响:随机对照试验

江静 刘成勇 方琴琴 秦珊 王晓秋 徐亮 万青云 吴文忠

针刺研究2024,Vol.49Issue(11):1174-1180,7.
针刺研究2024,Vol.49Issue(11):1174-1180,7.DOI:10.13702/j.1000-0607.20230778

电针对慢性失眠症患者脑电特征信号的影响:随机对照试验

Effect of electroacupuncture on the characteristic signal of electroencephalogram in the patients with chronic insomnia:a randomized controlled trial

江静 1刘成勇 1方琴琴 1秦珊 1王晓秋 2徐亮 3万青云 1吴文忠1

作者信息

  • 1. 南京中医药大学附属医院针灸康复科,南京 210029
  • 2. 南京中医药大学附属医院治未病科,南京 210029
  • 3. 南京中医药大学附属医院脑电图室,南京 210029
  • 折叠

摘要

Abstract

Objective To observe the effect of electroacupuncture(EA)on sleep quality and electroencephalogram(EEG)signal in the patients with chronic insomnia and to explore its mechanism.Methods Sixty patients with chronic insomnia were randomized into an EA group(30 cases,3 cases dropped out)and a health learning group(30 cases,3 cases dropped out).In the health learning group,the sleep health education was provided.In the EA group,besides the health education as the health learning group,EA was delivered at Baihui(GV20),Yintang(GV24+),bilateral Shenmen(HT7),bilateral Sanyinjiao(SP6),with continuous wave,2 Hz in frequency,once every other day,and 3 interventions a week.EA was given for 4 weeks successi-vely,composed of 12 treatments.The score of Pittsburgh sleep quality index(PSQI),Hamilton anxiety scale(HAMA),and patient health questionnaire-9(PHQ-9)before and after treatment were compared between the two groups.The EEG signals were collected and the relative power and entropy of EEG before and after treatment were compared between the two groups.Results After treatment,the scores of PSQI,HAMA and PHQ-9,the relevant power of β wave in F8 and T3 channels,and that of α wave in T4 channel,and the entropy in T3 channel under the eyes-open(EO)resting state,as well as the relevant power and the entropy of y wave in F8 channel under the eyes-closed(EC)resting state in the EA group were lower(P<0.05)than those before the treatment.All of the above results were lower than those of the health learning group at the same time points(P<0.05).Under the EO resting state,the relevant power of the θ and δ waves of T3 channel and θ wave of T4,O2 and Pz channels of patients in the EA group after the treatment were increased(P<0.05)than those before the treatment,and higher(P<0.05)than those of the health learning group at the same time points.Conclusion Acupuncture is effective on chronic insomnia,which may be related to the regulation EEG signals.

关键词

慢性失眠症/电针/睡眠质量/脑电信号/随机对照试验

Key words

Chronic insomnia/Electroacupuncture/Sleep quality/Electroencephalogram/Randomized controlled trial

引用本文复制引用

江静,刘成勇,方琴琴,秦珊,王晓秋,徐亮,万青云,吴文忠..电针对慢性失眠症患者脑电特征信号的影响:随机对照试验[J].针刺研究,2024,49(11):1174-1180,7.

基金项目

国家自然科学基金项目(No.82274631) (No.82274631)

2021年江苏省重点研发计划(社会发展)项目(No.SBE2021750258) (社会发展)

2021年度院级创新发展基金专项(No.Y2021CX13) (No.Y2021CX13)

针刺研究

OA北大核心CSTPCDMEDLINE

1000-0607

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