针刺研究2024，Vol.49Issue(11)：1220-1225,6.DOI:10.13702/j.1000-0607.20230591
针刺治疗癌性疼痛的镇痛机制研究进展
Research progress on analgesic mechanism of acupuncture for cancer pain
摘要
Abstract
Cancer pain is one of the common complications in patients with intermediate or advanced cancer,which brings severe sufferings to patients and their families,and also seriously interferes with the anti-tumor process.Acupuncture is an effective method for the treatment of cancer pain,which has the advantages of simple operation,quick effect and fewer side effects,and is widely used in clinic.In this paper,we reviewed the relevant literature on the mechanisms of acupuncture in the treatment of cancer pain both at home and abroad in recent years,and summarized the analgesic mechanisms of acupuncture for cancer pain from the peripheral level and the central level.It is found that acupuncture can relieve cancer pain by regulating immune inflammatory response,expression of ion channels and pain-related receptors,remising central sensitization,activating endogenous pain modulating system and suppressing pain transmission pathways.In addition,we also think that the use of high-throughput multi-omics techniques and neuroimaging methods to detect and analyze the brain areas or body fluids before and after acupuncture should be the focus of acupuncture analgesia research in the future.关键词
针刺/癌性疼痛/研究进展/机制Key words
Acupuncture/Cancer pain/Research progress/Mechanism引用本文复制引用
吴建丽,覃建峰,覃建雄,程彩红,孙忠人,覃迅云..针刺治疗癌性疼痛的镇痛机制研究进展[J].针刺研究,2024,49(11):1220-1225,6.基金项目
国家自然科学基金资助项目(No.82105030) （No.82105030）
黑龙江省博士后资助经费面上项目(No.LBH-Z22253) （No.LBH-Z22253）
