中国临床药学杂志2024，Vol.33Issue(10)：726-732,7.DOI:10.19577/j.1007-4406.2024.10.002
药师主导的智能微信群在癫痫患者用药宣教中的效果评价
Evaluation of the medication education effect of smart WeChat group led by pharmacists for patients with epilepsy
摘要
Abstract
AIM To study the education effect of the smart WeChat group led by pharmacists for patients with epilepsy who need long-term medication and their needs for pharmaceutical care.METHODS A randomized controlled research was conducted to include adult patients who had been diagnosed with epilepsy and started the therapy of anti-seizure medications(ASMs).After face-to-face education,the patients were randomly divided into conventional education group and smart WeChat education group.WeChat group provided education by short texts daily and short videos weekly.There was a pharmacist and 2 physicians in the group who were responsible for answering the other questions raised by patients.There was also a keyword-matching auto-response function.For example,by entering the corresponding number,users could automatically receive links to private chat programs,clinic appointments and more knowledge about epilepsy.After the 3-month follow-up,the frequency of seizures,high compliance rate,and medication knowledge were compared between the overall population and subgroup patients.Pharmacists were responsible for collecting and classifying questions from all patients in the group.RESULTS There were 64 patients enrolled in each group.The seizure-free rate,high compliance(8 points)rate and medication knowledge(＞30 points)rate in conventional group and smart WeChat education group was 49％and 63％(P=0.128),38％and 47％(P=0.427),20％and 34％(P=0.085),respectively,with no statistically significant differences.In the subgroup analysis,the seizure-free rate of patients under the age of 60 years or with high school education in the smart WeChat education group was significantly higher than those in the conventional education group(OR=2.67,95％CI 1.12-6.34;OR=4.42,95％CI 1.21-16.12).Regarding compliance,patients who took multiple ASMs in the smart WeChat education group had significantly higher compliance than those in the conventional education group(OR=3.40,95％CI 1.07-10.77).When answering the knowledge questionnaire,patients under the age of 60,male patients or those who took multiple ASMs scored higher than 30 points than the conventional education group(OR=3.59,95％CI 1.01-12.73,OR=2.67,95％CI 1.03-6.89 and OR=4.58,95％CI 1.08-19.38).CONCLUSION Patients with epilepsy under the age of 60 years and taking multiple ASMs can benefit more from the smart WeChat group education,such as increasing their knowledge of the disease and medication,as well as their compliance,thereby improving the possibility of being seizure-free.However,more randomized controlled studies with more patients are needed to confirm the point.Since patients with epilepsy have a high demand for information about drug combinations,cough and cold drugs,digestive tract and metabolic drugs,more popular science education should be conducted in these aspects.关键词
微信群/癫痫/宣教/依从性/科普话题Key words
WeChat group/epilepsy/patient education/medication compliance/topical issue引用本文复制引用
潘雯,徐勤霞,丁晶,吴轶,李晓宇..药师主导的智能微信群在癫痫患者用药宣教中的效果评价[J].中国临床药学杂志,2024,33(10):726-732,7.基金项目
中国药学会科技开发中心科普项目(编号CMEI2022KPYJ00561) （编号CMEI2022KPYJ00561）
复旦大学附属中山医院青年科学基金(编号2021ZSQN68) （编号2021ZSQN68）
