中国临床药学杂志2024，Vol.33Issue(10)：739-745,7.DOI:10.19577/j.1007-4406.2024.10.004
基于TIDieR检查表评估住院患者临床药学服务随机对照试验的报告质量
Evaluation of the completeness on randomized controlled trials of clinical pharmacist intervention in hospitalised patients based on TIDieR checklist
摘要
Abstract
AIM To assess the adequacy of published Cochrane systematic reviews and clinical pharmacist intervention randomized controlled trial(RCT)reports included in China National Knowledge Infrastructure using the Template for Intervention Description and Replication(TIDieR)checklist,so as to identify areas for improvement,assist clinical pharmacists to design RCTs of pharmaceutical care more effectively,and improve the quality of intervention reports.METHODS A secondary analysis was conducted on the studies included in Cochrane systematic reviews that evaluated the impact of drug intervention measures on the outcomes of hospitalized patients,and RCTs of clinical pharmacist intervention reports published in CNKI over the past 5 years were searched.The completeness of reporting was independently assessed by 2 researchers using the 15 items from the TIDieR checklist.RESULTS A total of 91 studies were included in the analysis.The study sample sizes ranged from 47 patients to 330 patients.The included studies involved diverse intervention methods,among which medication education(46 studies,50.55％),patient-oriented studies(58 studies,63.74％),and cardiovascular disease-related studies(25 studies,27.47％)were the most common.None of the studies reported on all checklist items.Among the 15 items,none reached a reporting rate of 100％,while only items 2a and 5b had detailed reporting rates exceeding 80％.The items with reporting rates below 20％were item 5a(18.68％),item 5c(13.19％),item 9(4.40％),and item 10(5.49％).Principal component analysis showed that the description of intervention implementation methods(items 3,4,6,7,and 8)and the background and training of intervention implementers(items 5a and 5c)had a greater impact on report quality.CONCLUSION The overall quality of reporting in published RCTs on pharmaceutical care requires enhancement,particularly focusing on the adequacy,completeness,and detail of the intervention measures.In the future,researchers can refer to the TIDieR checklist requirements when designing and writing clinical pharmacy intervention reports to ensure a thorough and detailed account of the complete intervention details.Thus,the credibility and replicability of research can be improved,and the standardized development of clinical pharmacy services can be promoted.关键词
TIDieR检查表/临床药师/药学服务/随机对照试验/研究报告Key words
TIDieR checklist/clinical pharmacist/pharmaceutical care/randomized controlled trial/research report引用本文复制引用
张春娟,洪煜璐,周昔程,马秀娟..基于TIDieR检查表评估住院患者临床药学服务随机对照试验的报告质量[J].中国临床药学杂志,2024,33(10):739-745,7.基金项目
海盐县卫健局卫生科技计划项目(编号2021wsyb008) （编号2021wsyb008）
