中国脑血管病杂志2024，Vol.21Issue(10)：714-720,封3,8.DOI:10.3969/j.issn.1672-5921.2024.10.011
白细胞介素33/血清刺激素2信号通路在缺血性卒中中的研究进展
Research progress on the role of IL-33/ST2 signaling pathway in ischemic stroke
摘要
Abstract
Ischemic stroke has always been a thorny problem in the field of cerebrovascular research due to its complex injury mechanism,high incidence,and disability rate.It is essential to find new and effective interventions and neuroprotective strategies.Interleukin-33(IL-33),as one of the newly discovered members of the IL-1 family,is currently the focus of global academic research,and serum stimulation-2(ST2)is the main receptor for its action.In this paper,the current research status of the IL-33/ST2 signaling pathway in ischemic stroke was reviewed,to clarify the protective mechanism of IL-33/ST2 signaling pathway in ischemic stroke,including amplification of regulatory T cell,regulation of inflammation,and improvement of white matter,to provide new ideas for the treatment of ischemic stroke.关键词
缺血性卒中/白细胞介素33/IL-33/ST2信号通路/综述Key words
Ischemic stroke/Interleukin-33/IL-33/ST2 signaling pathway/Review引用本文复制引用
鲁霞,吴洁,党银霞,王生霞,王凡..白细胞介素33/血清刺激素2信号通路在缺血性卒中中的研究进展[J].中国脑血管病杂志,2024,21(10):714-720,封3,8.基金项目
吴阶平医学基金会科研项目(320.6750.2023-24-3) （320.6750.2023-24-3）
