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胃癌腹膜转移伴腹腔积液的治疗策略

马君俊 李树春 臧潞

中国实用外科杂志2024,Vol.44Issue(10):1120-1125,6.
中国实用外科杂志2024,Vol.44Issue(10):1120-1125,6.DOI:10.19538/j.cjps.issn1005-2208.2024.10.08

胃癌腹膜转移伴腹腔积液的治疗策略

Treatment strategies for gastric cancer with peritoneal metastasis and ascites

马君俊 1李树春 1臧潞1

作者信息

  • 1. 上海交通大学医学院附属瑞金医院普通外科 上海市微创外科临床医学中心,上海 200025
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摘要

Abstract

The incidence of gastric cancer peritoneal metastases is high,and the prognosis is poor,with a median survival time often less than one year.Currently,the diagnosis of peritoneal metastases primarily relies on imaging tests,but diagnosing occult peritoneal metastases remains challenging.Laparoscopic exploration not only allows direct visualization of metastatic lesions but also enables histological and cytological examinations,making it a routine method for diagnosing gastric cancer peritoneal metastases.The treatment of gastric cancer peritoneal metastases is a hot research topic.Due to the presence of the plasma-peritoneal barrier,systemic therapy alone has limited efficacy for gastric cancer peritoneal metastases,and in recent years,various intraperitoneal local treatments have gained increasing attention.Treatments represented by neoadjuvant intraperitoneal and systemic chemotherapy(NIPS)have shown promise in improving symptoms for some gastric cancer peritoneal metastases patients with moderate ascites,converting them to a resectable state,and ultimately prolonging survival.Selecting appropriate treatment methods and timing based on the severity of gastric cancer peritoneal metastases remains a focus of future research.

关键词

胃癌/腹膜转移/腹腔积液/腹腔灌注化疗

Key words

gastric cancer/peritoneal metastasis/ascites/intraperitoneal chemotherapy

分类

临床医学

引用本文复制引用

马君俊,李树春,臧潞..胃癌腹膜转移伴腹腔积液的治疗策略[J].中国实用外科杂志,2024,44(10):1120-1125,6.

基金项目

国家自然科学基金面上项目(No.82372933) (No.82372933)

中央高校基本科研业务费专项基金资助(No.YG2023ZD03) (No.YG2023ZD03)

中国实用外科杂志

OA北大核心CSTPCD

1005-2208

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