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术前内镜下钛夹定位联合术中内镜和冰冻病理检查用于食管胃结合部腺癌腹腔镜手术切缘判定价值研究

杨瑞 齐韶铭 胡文庆 刘晖 宋东阳 崔鹏 魏伟 宗亮 乔鋆 王楠 王博 徐泽坤

中国实用外科杂志2024,Vol.44Issue(10):1155-1158,4.
中国实用外科杂志2024,Vol.44Issue(10):1155-1158,4.DOI:10.19538/j.cjps.issn1005-2208.2024.10.15

术前内镜下钛夹定位联合术中内镜和冰冻病理检查用于食管胃结合部腺癌腹腔镜手术切缘判定价值研究

Application of preoperative endoscopic titanium clip positioning combined with intraoperative endoscopy and quick-frozen pathology to the margin determination in laparoscopic surgery for adenocarcinoma of the esophagogastric junction

杨瑞 1齐韶铭 2胡文庆 3刘晖 3宋东阳 3崔鹏 3魏伟 3宗亮 3乔鋆 3王楠 3王博 2徐泽坤2

作者信息

  • 1. 山西医科大学附属运城市中心医院消化内科,山西运城 044099
  • 2. 长治医学院研究生处,山西长治 046000
  • 3. 山西省恶性肿瘤(食管胃结合部癌)临床医学研究中心长治医学院附属医院长治市人民医院胃肠外科,山西长治 046099
  • 折叠

摘要

Abstract

Objective To preliminarily explore the application value of preoperative titanium clip positioning combined with intraoperative endoscopy and intraoperative quick-frozen pathology for the margin analysis in laparoscopic surgery for adenocarcinoma of the esophagogastric junction(AEG).Methods A retrospective analysis was conducted on the clinical data of 133 patients who underwent laparoscopic surgery for AEG between January 2021 and December 2022 at Changzhi People's Hospital.All patients received preoperative titanium clip positioning,intraoperative endoscopy,and intraoperative quick-frozen pathology margin analysis.Observational indicators included:Intraoperative endoscopic positioning time,the first positive resection margin rate,postoperative complications,postoperative hospital stay,rate of unplanned reoperations during the perioperative period,and mortality rate.Results The mean intraoperative endoscopic positioning time was(4.2±1.3)min,with an average time of 7.4 minutes for the first 6 cases.The first positive resection margin rate was 3.0%,but all were negative upon the second examination.No anastomotic leakage or other complications occurred intraoperatively.Postoperatively,4 patients(3.0%)experienced hoarseness and sore throat,with 1 case of partial subluxation of the left cricoarytenoid joint,which resolved after treatment.12 patients developed complications classified as Clavien-Dindo grade ≥ Ⅲ,with an overall complication rate of 9.0%.All patients recovered with conservative treatment,without the need for secondary surgery,and no perioperative mortality was observed.The mean hospital stay was(12.0±4.7)d.Conclusion Preoperative endoscopic titanium clip positioning combined with intraoperative endoscopy and quick-frozen pathology margin analysis can potentially enable precise tumor resection and achieve negative surgical margins in laparoscopic A EG surgery.

关键词

食管胃结合部腺癌/腹腔镜/切缘定位/术中内镜/钛夹定位

Key words

adenocarcinoma of esophagogastric junction/laparoscopy/resection margin positioning/intraoperative gastroscopy/titanium clip positioning

分类

医药卫生

引用本文复制引用

杨瑞,齐韶铭,胡文庆,刘晖,宋东阳,崔鹏,魏伟,宗亮,乔鋆,王楠,王博,徐泽坤..术前内镜下钛夹定位联合术中内镜和冰冻病理检查用于食管胃结合部腺癌腹腔镜手术切缘判定价值研究[J].中国实用外科杂志,2024,44(10):1155-1158,4.

基金项目

山西省卫健委四个一批-重大科技攻关专项项目(No.2022XM02) (No.2022XM02)

吴阶平医学基金会项目(No.320.6750.2020-11-6) (No.320.6750.2020-11-6)

中国实用外科杂志

OA北大核心CSTPCD

1005-2208

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