摘要
Abstract
Objective:To investigate the clinical effect of craniotomy clipping by lateral supraorbital approach in the treatment of patients with ruptured anterior circulation aneurysm.Method:A total of 100 patients with ruptured anterior circulation aneurysm who received craniotomy clipping treatment in Jinjiang City Hospital from January 2020 to December 2023 were divided into control group(n=50)and observation group(n=50)according to random number table method.The control group was treated with craniotomy clipping by pterion approach,and the observation group was treated with craniotomy clipping by lateral supraorbital approach.The treatment effect,intraoperative blood loss,operative time,hospital stay,complication rate,before and after surgery of neurological function scores[national institutes of health stroke scale(NIHSS)score],nerve injury indexes[neuron specific enolase(NSE),S100 calcium-binding protein B(S100B)and myelin basic protein(MBP)]and traumatic stress indexes[β-endorphin(β-EP),interleukin-6(IL-6)and dynorphin A1-13(DynA1-13)]were compared between two groups.Result:Three months after operation the total effective rate of the observation group was significantly higher than that of the control group,the intraoperative blood loss was significantly lower than that of the control group,and the operation time and hospital stay were significantly shorter than those of the control group,the differences were statistically significant(P<0.05).There were no significant differences in the incidence of complications between two groups(P>0.05).There were no significant differences in NIHSS scores,nerve injury indexes and traumatic stress indexes between two groups before surgery(P>0.05).Seven days after operation,the NIHSS scores,nerve injury indexes and traumatic stress indexes in the observation group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:Craniotomy clipping by lateral supraorbital approach has good clinical effect in the treatment of ruptured anterior circulation aneurysm,which can effectively control nerve injury and body traumatic stress,and promote postoperative recovery of patients.关键词
眶上额外侧入路/翼点入路/开颅夹闭/前循环动脉瘤破裂Key words
Lateral supraorbital approach/Pterion approach/Craniotomy clipping/Ruptured anterior circulation aneurysm
