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腹腔镜直肠癌根治术中保留左结肠动脉对直肠癌患者术后恢复情况及T淋巴细胞亚群的影响

陈军 高杰 郭毅蓉 上官少华

中国医学创新2024,Vol.21Issue(28):117-120,4.
中国医学创新2024,Vol.21Issue(28):117-120,4.DOI:10.3969/j.issn.1674-4985.2024.28.027

腹腔镜直肠癌根治术中保留左结肠动脉对直肠癌患者术后恢复情况及T淋巴细胞亚群的影响

The Effect of Preserving the Left Colon Artery during Laparoscopic Radical Resection of Rectal Cancer on Postoperative Recovery and T Lymphocyte Subsets in Rectal Cancer Patients

陈军 1高杰 1郭毅蓉 1上官少华1

作者信息

  • 1. 福建省南平市第一医院胃肠外科 福建 南平 353000
  • 折叠

摘要

Abstract

Objective:To analyze the impact of preserving the left colon artery during laparoscopic radical resection of rectal cancer on rectal cancer patients.Method:Eighty patients with rectal cancer admitted to the Gastrointestinal Department of the First Hospital of Nanping City,Fujian Province from May 2022 to May 2023 were selected as the study subjects.They were randomly divided into two groups using a random number table method,with 40 patients in each group.All patients underwent laparoscopic radical resection for rectal cancer.The control group did not retain the left colon artery during surgery,while the observation group retained the left colon artery during surgery.The surgical outcomes,postoperative recovery,gastrointestinal hormones,T lymphocyte subsets,and complications between the two groups were compared.Result:There were no significant differences in the operation situation(intraoperative blood loss,operation time,number of lymph node dissection),postoperative recovery(anal exhaust time,catheter indwelling time,hospitalization time)and complications between two groups(P>0.05).3 d after surgery,the MTL of the observation group was(95.36±10.53)pg/mL,and the GAS was(268.97±15.49)pg/mL,which were higher than(72.48±8.69)pg/mL and(233.64±13.20)pg/mL of the control group,the incidence of complications in the observation group was lower than that in the control group,the differences were all statistically significant(P<0.05).Before surgery and 3 d after surgery,there were no significant differences in the levels of CD3+,CD4+and CD8+between two groups(P>0.05).Conclusion:Preservation of the left colon artery during laparoscopic radical resection of rectal cancer can promote postoperative gastrointestinal function recovery in patients with rectal cancer,with no serious complications and minimal impact on their immune function.

关键词

直肠癌/并发症/T淋巴细胞亚群/胃肠激素/免疫功能

Key words

Rectal cancer/Complications/T lymphocyte subpopulations/Gastrointestinal hormones/Immunologic function

引用本文复制引用

陈军,高杰,郭毅蓉,上官少华..腹腔镜直肠癌根治术中保留左结肠动脉对直肠癌患者术后恢复情况及T淋巴细胞亚群的影响[J].中国医学创新,2024,21(28):117-120,4.

中国医学创新

1674-4985

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