中国医学创新2024，Vol.21Issue(29)：179-183,5.DOI:10.3969/j.issn.1674-4985.2024.29.040
光动力疗法联合免疫治疗在恶性肿瘤中的研究进展
Research Progress of Photodynamic Therapy Combined with Immunotherapy in Malignant Tumors
田丹 1夏思雨 2李里1
作者信息
- 1. 哈尔滨医科大学附属第二医院肿瘤内科 黑龙江 哈尔滨 150081
- 2. 北大荒集团总医院肿瘤科 黑龙江 哈尔滨 150006
- 折叠
摘要
Abstract
Photodynamic therapy(PDT)is a non-invasive and highly selective tumor treatment that uses light of the appropriate wavelength to activate photosensitizer and produce instantaneous level reactive of oxygen species(ROS)to kill tumor cells and blood vessels around the tumor,thereby achieving therapeutic effects.In recent years,it has been confirmed that PDT can not only induce the local immune response of tumors,but also play a key role in the establishment of adaptive immunity.In addition,recent studies have found that PDT combined with immunotherapy has a synergistic effect.This article reviews the mechanism of immune response induced by PDT,as well as the current related basic research and clinical research status of PDT combined with immunotherapy.关键词
光动力治疗/免疫调节/免疫治疗Key words
Photodynamic therapy/Immunomodulation/Immunotherapy引用本文复制引用
田丹,夏思雨,李里..光动力疗法联合免疫治疗在恶性肿瘤中的研究进展[J].中国医学创新,2024,21(29):179-183,5.
