中国医学创新2024,Vol.21Issue(30):183-188,6.DOI:10.3969/j.issn.1674-4985.2024.30.042
临床常规指标对脓毒症急性肾损伤发生的预测研究
Prediction of the Occurrence of Sepsis Acute Kidney Injury by Clinical Routine Indexes
摘要
Abstract
Acute kidney injury(AKI)is one of the most commonly involved organs of sepsis,and the incidence and mortality of S-AKI are high.At present,the diagnosis of S-AKI mainly relies on the monitoring of serum creatinine or urine volume,but creatinine and urine volume are susceptible to some factors,which makes the early diagnosis of S-AKI limited.Although a large number of novel biomarkers have been identified,they are rare,complex and expensive to detect in the clinic,and their effectiveness still needs to be validated by extensive clinical trials.The conventional clinical indicators make up for the defects of the new markers in early screening,and the research on the pathophysiological mechanism of S-AKI has also achieved remarkable results.This article reviews the pathophysiological mechanism of S-AKI and the progress in predicting the occurrence of S-AKI by conventional clinical indicators,aiming to provide some help for better clinical understanding and prevention of S-AKI.关键词
脓毒症/急性肾损伤/预测Key words
Sepsis/Acute kidney injury/Prediction引用本文复制引用
黄超,段盈霜,马骏麒,姜雯娟..临床常规指标对脓毒症急性肾损伤发生的预测研究[J].中国医学创新,2024,21(30):183-188,6.基金项目
新疆维吾尔自治区自然科学基金资助项目(2022D01C544) (2022D01C544)