清热利胆颗粒辅助治疗胆囊穿刺引流术后腹腔镜胆囊切除术疗效观察OA北大核心CSTPCD

Objective To observe the clinical efficacy of Qingre Lidan Granules(QRLDG)for assisting treatment in laparoscopic cholecystectomy(LC)of acute cholecystitis(AC)patients after percutaneous transhepatic gallbladder drainage(PTGD).Methods A retrospective collection was conducted on 3 061 AC patients at First Affiliated Hospital of Dalian Medical University from January 2018 to April 2023.Of them,159 met the inclusion criteria.All the patients were assigned to the observation group(50 cases)and the control group(109 cases)according to whether used QRLDG after PTGD.Patients in the control group received conventional Western medicine,while those in the observation group additionally took QRLDG.The duration of LC surgery,intraoperative bleeding volume,number of cases of LC conversion to open surgery,number of cases of gallbladder necrosis or abscess,number of cases of difficult LC(surgery time ≥ 90 min or difficulty in dissecting the gallbladder triangle),postoperative complications of LC,placement of drainage tubes,placement time of drainage tubes,length of hospital stay,postoperative hospitalization days,and hospitalization expenses were observed.Results Compared with the control group,LC surgery time,intraoperative bleeding volume,and difficulty in LC were shorter in the observation group(P＜0.05,P＜0.01).Postoperative hospitalization days,placement rate of postoperative drainage tube,and hospitalization expenses were lesser in the observation group than in the control group(P＜0.05).There was no statistical difference in the incidence of postoperative complications between the two groups(P＞0.05).Conclusion For AC patients after PTGD,additional use of QRLDG effectively improved the safety of LC surgery,shortened the surgical time,reduced perioperative bleeding,decreased the placement rate of drainage tubes,helped post-operative recovery,and lowered post-operative hospitalization time and expenses.