组织工程与重建外科杂志2024，Vol.20Issue(5)：503-506,4.DOI:10.3969/j.issn.1673-0364.2024.05.001
皮肤再生"星舰":探索ADM在扩张技术中的应用突破与潜能
"Starship" in skin regeneration:Exploring the breakthroughs and potential of acellular dermal matrix applied in skin expansion
摘要
Abstract
The simultaneous reconstruction of appearance and function following large-area skin defects remains an unresolved challenge in clinical practice.Although skin expansion technology has been widely employed in tissue repair and reconstruction,its development has stagnated,primarily due to low expansion efficiency,high complication rates,and poorly understood mechanisms.To address this issue,an innovative approach utilizing acellular dermal matrix was proposed to assist in skin expansion and achieved promising preliminary clinical results.Acellular dermal matrix provides a "biocompatible" interface,balances mechanical forces,and serves as an active scaffold to support various cell types.However,its specific mechanism of action during the skin expansion process warrants further investigation.By acting as an expansion companion,acellular dermal matrix synergistically enhances skin expansion and holds the potential to break through current expansion limitations,thereby unlocking the full potential of skin expansion technology.关键词
皮肤扩张/脱细胞真皮基质/真皮再生/机械牵张Key words
Skin expansion/Acellular dermal matrix/Dermis regeneration/Mechanical stretch分类
医药卫生引用本文复制引用
罗旭松..皮肤再生"星舰":探索ADM在扩张技术中的应用突破与潜能[J].组织工程与重建外科杂志,2024,20(5):503-506,4.基金项目
国家自然科学基金(82372536) （82372536）
上海市自然科学基金(19ZR1430100) （19ZR1430100）
上海市科学技术委员会临床医学研究中心项目(22MC1940300). （22MC1940300）
