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改性羟基磷灰石基骨修复材料的研究进展

黄磊云 白正林 符光捷 华闻达 孟增东

组织工程与重建外科杂志2024,Vol.20Issue(5):568-573,6.
组织工程与重建外科杂志2024,Vol.20Issue(5):568-573,6.DOI:10.3969/j.issn.1673-0364.2024.05.012

改性羟基磷灰石基骨修复材料的研究进展

Research progress on modified hydroxyapatite-based bone repair materials

黄磊云 1白正林 1符光捷 1华闻达 1孟增东2

作者信息

  • 1. 650500 云南省昆明市 昆明理工大学医学院
  • 2. 650500 云南省昆明市 昆明理工大学医学院||650032 云南省昆明市 云南省第一人民医院
  • 折叠

摘要

Abstract

As a kind of biomedical material,modified hydroxyapatite-based material has good mechanical properties,biocompatibility and osteoinductive ability.It has the advantages of similar composition with natural bone,not easy to cause immune rejection,good biological activity and compatibility,non-toxic,degradable,easy to prepare and process,and makes up for the shortcomings of natural bone material transplantation.In this paper,the biological modification,physicochemical modification and composite modification methods of the material were introduced,and the effects of different modification methods on the properties of the material were compared.In addition,the current problems and challenges of modified hydroxyapatite-based material were presented in the discussion section,and the future development of this kind of material was also prospected.

关键词

改性材料/羟基磷灰石/生物相容性/力学性能/抗菌性/降解性

Key words

Modified materials/Hydroxyapatite/Biocompatibility/Mechanical properties/Antibacterial properties/Degradability

分类

医药卫生

引用本文复制引用

黄磊云,白正林,符光捷,华闻达,孟增东..改性羟基磷灰石基骨修复材料的研究进展[J].组织工程与重建外科杂志,2024,20(5):568-573,6.

基金项目

云南省卫生健康委员会医学领军人才培养计划(L-218004) (L-218004)

云南省兴滇英才支持计划名医专项(XDYC-MY-2022-0027) (XDYC-MY-2022-0027)

云南省骨科与运动康复临床医学研究中心项目(202102AA310068) (202102AA310068)

云南省脊柱脊髓疾病临床医学中心项目(ZX2022000101). (ZX2022000101)

组织工程与重建外科杂志

OACSTPCD

1673-0364

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